About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

'Communication' Important for Storage of Memories

by Hannah Joy on October 31, 2017 at 11:58 AM
Font : A-A+

'Communication' Important for Storage of Memories

An innovative "NeuroGrid" technology used shows that sleep can increase communication between two brain areas, which plays a major role in memory storage, reveals a new study.

The work, published in Science, was partially funded by the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, a project of the National Institutes of Health devoted to accelerating the development of new approaches to probing the workings of the brain.

Advertisement


"Using new technologies advanced by the BRAIN Initiative, these researchers made a fundamental discovery about how the brain creates and stores new memories," said Nick Langhals, Ph.D., program director at NIH's National Institute of Neurological Disorders and Stroke.

A brain structure called the hippocampus is widely thought to turn new information into permanent memories while we sleep. Previous work by the new study's senior author, New York University professor György Buzsáki, M.D., Ph.D., revealed high-frequency bursts of neural firing called ripples in the hippocampus during sleep and suggested they play a role in memory storage.
Advertisement

The current study confirmed the presence of ripples in the hippocampus during sleep and found them in certain parts of association neocortex, an area on the brain's surface involved in processing complex sensory information.

"When we first observed this, we thought it was incorrect because it had never been observed before," said Dion Khodagholy, Ph.D., the study's co-first author and assistant professor at Columbia University in New York.

Using a cutting-edge NeuroGrid system they invented, along with recording electrodes placed deeper into the brain, the researchers examined activity in several parts of rats' brains during non-rapid eye movement (NREM) sleep, the longest stage of sleep.

Their NeuroGrid consists of a collection of tiny electrodes linked together like the threads of a blanket, which is then laid across an area of the brain so that each electrode can continuously monitor the activity of a different set of neurons.

"This particular device allows us to look at multiple areas of the brain at the same time," said Jennifer Gelinas, M.D., Ph.D., the study's co-first author and assistant professor at Columbia University.

The team was also surprised to find that the ripples in the association neocortex and hippocampus occurred at the same time, suggesting the two regions were communicating as the rats slept. Because the association neocortex is thought to be a storage location for memories, the researchers theorized that this neural dialogue could help the brain retain information.

To test that idea, they examined brain activity during NREM sleep in rats trained to locate rewards in a maze and in rats that explored the maze in a random fashion.

In the latter group of animals, the ripples in the hippocampus and cortex were no more synchronized before exploring the maze than afterwards.

In the trained rats, the learning task increased the cross-talk between those areas, and a second training session boosted it even more, further suggesting that such communication is important for the creation and storage of memories.

The group hopes to use the NeuroGrid in people undergoing brain surgery for other reasons to determine if the same ripples occur in the human brain. The researchers also plan to investigate if manipulating that neural firing in animals can boost or suppress memory formation in order to confirm that ripples are important for that process.

"Identifying the specific neural patterns that go along with memory formation provides a way to better understand memory and potentially even address disorders of memory," said Dr. Gelinas.



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Turmeric: Magic Ingredient to Keep you Healthy in Winter
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.


Recommended Reading
Foods to Improve Memory Power
Eating healthy nutritious foods can help improve memory power and prevent brain-related illness. ......
Brain Exercises to Improve Memory
An active brain can certainly help in improving memory by strengthening the connections between ......
Brominated Vegetable Oil
Brominated Vegetable Oil (BVO) is a chemical product derived from vegetable oil. Although it poses ....
7 Ways How Writing by Hand Improves Brain Power
Do you want to sharpen the way your brain works? Try writing by hand to sharpen your mind and ......

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use