Common Toothpaste Ingredient can Make Antibiotics Less Effective

UTIs occur when bacteria, primarily Escherichia coli (E. coli), enter and infect the urinary tract. Antibiotics such as Cipro are commonly used to kill the bacteria and treat the infection.

Advertisement

UTIs are common, so is exposure to triclosan. About 10 percent of adults have levels high enough to prevent E. coli from growing.

In the study the team examined whether triclosan's presence in the body interferes with treating UTIs.

They found that mice which drink triclosan-spiked water have urine triclosan levels similar to those reported in humans.

"This result meant we could actually test the impact that human urine levels of triclosan have during antibiotic treatment of UTIs in mice," said Petra Levin, Professor at the varsity.

After antibiotic treatment, mice with triclosan exposure had a large number of bacteria in their urine and stuck to the bladder, but mice without exposure had significantly lower bacterial counts.

They found 100 times more bacteria in the urine of triclosan-treated mice, suggesting that antibiotics are less effective at treating UTIs when triclosan is around.

Source: IANS