About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Common Fibre 'Pectin' Helps to Kill Prostate Cancer Cells

by VR Sreeraman on August 21, 2007 at 12:47 PM
Font : A-A+

Common Fibre 'Pectin' Helps to Kill Prostate Cancer Cells

A new study has found that a type of fibre found in fruits and vegetables kill prostate cancer cells.

The fibre 'pectin' is also an ingredient in jams and other food products.

Advertisement

The study conducted by University of Georgia found that exposing prostate cancer cells to pectin under laboratory conditions reduced the number of cells by up to 40 percent.

UGA Cancer Center researcher Debra Mohnen and her colleagues at UGA, along with Vijay Kumar, chief of research and development at the VA Medical Center in Augusta, found that the cells literally self-destructed in a process known as apoptosis. Pectin even killed cells that aren't sensitive to hormone therapy and therefore are difficult to treat with current medications.
Advertisement

"What this paper shows is that if you take human prostate cancer cells and add pectin, you can induce programmed cell death. If you do the same with non-cancerous cells, cell death doesn't occur," said Mohnen, a professor of biochemistry and molecular biology.

Mohnen's study adds to the growing body of evidence on the health benefits of pectin, which has been shown to lower cholesterol and glucose levels in humans. Cancer studies using rats and cell cultures have found that pectin can reduce metastasis and prevent lung and colon tumours.

Another study found that pectin induces apoptosis in colon cancer cells. Mohnen's is the first to show that pectin induces apoptosis in prostate cancer cells and brings scientists closer to understanding what makes the common component of plants an effective cancer fighter.

Mohnen and her team analyzed three different types of commercially available pectin and found large differences in anti-cancer activity. They found that treatment under mild base conditions decreased the anti-cancer properties of pectin while heat treatment significantly increased anti-cancer activity.

Pectin is one of nature's most complex molecules and has the potential to bind to several sites on cells and to elicit several different cellular responses at the same time. Mohnen and her team are working to identify the smallest structure within pectin that can induce apoptosis with the ultimate goal of developing pectin-based pharmaceuticals or foods with enhanced health benefits.

Mohnen said that more evidence is needed to support the use of specific pectin supplements, but said that most Americans would do well to increase their intake of fruits and vegetables.

"Even though we hear constantly that we're supposed to eat lots of fruits and vegetables, it wasn't until we started working on these studies that it finally hit home how really important that was," Mohnen said.

"By simply increasing your intake of fruits of vegetables, you're going to get a lot of pectin and you're going to get all of the other beneficial phytochemicals at the same time," Mohnen added.

The study is published in the August issue of the journal Glycobiology.

Source: ANI
SRM/J
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Prostate Cancer Cancer and Homeopathy Parkinsons Disease Surgical Treatment Trans-Urethral Resection of the Prostate Prostate Cancer Facts Cancer Facts Cancer Prostate Cancer: Treatment Options Prostate Specific Antigen [PSA] Nutrition All Men Need 

Recommended Reading
First Biomarker for Prostate Cancer Discovered
Mayo Clinic researchers have discovered the first immune molecule that plays a role in the ......
Broccoli and Cauliflower Slash Prostate Cancer Risks By Half
A new study says that eating cauliflower and broccoli twice a week, can almost halve a man's ......
Nutrition All Men Need
Everyone requires good nutrition, be it man, woman, child or elderly. However, nutrition that men ne...
Prostate Cancer
This cancer affects men over the age of 50 years and screening with rectal examination and PSA can h...
Prostate Cancer: Treatment Options
Treatment options of prostate cancer includes waiting, surgery, radiation, hormone therapy, chemothe...
Prostate Specific Antigen [PSA]
PSA blood test is specific to prostate gland but not necessarily a cancer specific test but is commo...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use