Medindia
Advertisement

Combining Bed Nets and Some Malaria Vaccines may Actually Worsen the Case

by Dr. Trupti Shirole on January 20, 2015 at 6:28 PM

 Combining Bed Nets and Some Malaria Vaccines may Actually Worsen the Case
Combining insecticide-treated bed nets with some malaria vaccines may actually worsen some cases of malaria rather than helping them, according to a new study by University of Michigan-led research team.

Researchers used a mathematical model of malaria transmission to find out what will happen when vaccines and bed nets are used together. Professor Mercedes Pascual, co-author of the study, said, "The joint use of bed nets and vaccines would not always lead to consistent increases in the efficacy of malaria control. Our study suggested that the combined use of some malaria vaccines with bed nets can lead to increased morbidity and mortality in older age classes."
Advertisement

Pre-erythrocytic vaccines (PEVs) aim to reduce the chances that a person will be infected when bitten by a disease-carrying mosquito. Blood-stage vaccines (BSVs) do not block infection but try to reduce the level of disease severity and the number of fatalities. Transmission-blocking vaccines (TBVs) do not protect vaccinated individuals against infection or illness, but prevent mosquitoes from spreading the disease to others after biting a vaccinated person.

Researchers found that the combination of treated bed nets and TBV vaccines achieves the most efficient control, resulting in fewer cases of malaria while increasing the probability of eliminating the disease. On the contrary, both BSV and PEV malaria vaccines, when combined with bed nets, actually increased the number of malaria cases seen in the modeling study. Interactions between the bed nets and BSV and PEV vaccines reduced levels of natural immunity in the population, increasing morbidity in older age classes.

The study will appear online in Proceedings of the National Academy of Sciences.

Source: Medindia
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
Plant-Based Diet may Reduce the Risk of COVID-19
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Malaria-water Malaria Mosquito Diseases Vaccination for Children Fever Top 10 Vaccine Myths Debunked Malaria - Protection Strategies 

Recommended Reading
Malaria
Malaria is caused by a parasite that enters blood through the bite of an infected mosquito. It is .....
Malaria - Waterborne
Encyclopedia section of medindia gives general information about About Malaria Causes...
Mosquito Diseases
Mosquito-borne diseases, like malaria, filaria, dengue, etc are common in places conducive of ......
New Herbal Remedy to Fight Malaria
Recent research has shown that the powdered dried leaves of Artemisia annua is much more effective ....
Fever
Fever or Pyrexia is an elevation in normal body temperature. Causes of fever include infections, inj...
Malaria - Protection Strategies
Malaria is a dangerous disease with lethal consequences that requires protective measures for preven...
Top 10 Vaccine Myths Debunked
Childhood vaccination has saved many lives, yet lots more has to be done to increase awareness and e...
Vaccination for Children
Vaccines are biological products that impart immunity to the recipient. Vaccines may be live attenua...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use