Combination Vaccines may Not Be So Painful

by Rajashri on Jul 13 2008 12:40 PM

As children head for the school their annual shots may not be so painful this time around.

This is due in large part to the growing trend of combining vaccines and booster shots into one or two injections, says Stephen Aronoff, M.D., chair and professor of pediatrics at Temple University’s School of Medicine.

Currently, children who are starting kindergarten (between ages 4-6) need a total of five shots: vaccines for diphtheria, tetanus and pertussis (DTaP), polio, measles, mumps and rubella (MMR), chicken pox, and hepatitis A. Children who are in day care need these plus an additional vaccine against Haemophilus influenza b (Hib).

“No one likes getting shots, but for young children especially, that’s a lot of needles,” Aronoff said.

In addition, before starting junior high or middle school (around age 11), children need to receive booster shots of all of these, and it is recommended they also have the vaccine for bacterial meningitis.

Aronoff says that the recent federal approval of Pentacel and Kinrix, two new combination vaccines that immunize infants and children against multiple diseases, will make it easier to fulfill school requirements with less stress to the patient.

Pentacel is a five-in-one vaccine meant to protect infants and children against diphtheria, tetanus, pertussis (whooping cough), polio and Hib. Kinrix is a four-in-one booster vaccine that is given to protect against diphtheria, tetanus, pertussis and polio.

While these vaccinations can be combined, Aronoff notes that there are still other vaccinations that children will need to get separately:

  • Flu vaccine - every year
  • Chicken pox – unless they have already contracted it or have gotten the required two doses
  • Meningitis
  • TDaP – if it has been more than five years since the last booster
He adds that at age 12, girls should get the Gardasil vaccine, which prevents the four major types of the human papilloma virus that can lead to cervical cancer.

“Previously, you couldn’t just mix vaccines together into one syringe; the volume would be much too big and many of the ingredients would counteract each other,” said Aronoff.

“But now we’re definitely going to see more about how vaccinations and booster shots can be combined. It’s more convenient and much easier for a child to sit still for one shot as opposed to four or five.”