About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Combination of Smoking and Obesity is Very Dangerous

by Kathy Jones on September 12, 2013 at 9:53 PM
Font : A-A+

 Combination of Smoking and Obesity is Very Dangerous

A new study has found that the combination of obesity and smoking could lead to more health problems compared to both factors separately.

The study was conducted by researchers at Pacific Northwest National Laboratory in Richland, Washington, and was focused on how the activity of P450 enzymes was affected by cigarette smoke. The P450 enzymes have already been found to interfere with the body's reaction to prescription medications while other studies have revealed that obesity was linked with changes in the P450 enzyme activity. The study has been presented at the 246th National Meeting and Exposition of the American Chemical Society (ACS)

Advertisement

For this study, the researchers exposed a group of mice to cigarette smoke, second-hand smoke or no smoke at all and observed its effect on P450 enzymes activity. The researchers found that cigarette smoke was linked with increased P450 enzyme activity though obese or normal weight of mice had no influence on the activity levels. However the combination of cigarette smoke and obesity did affect the activity of other enzymes, with obesity reducing the activity levels by 100 times.

"Our research shows that smoking and obesity together may pose a triple health threat in addition to the increased risks for heart disease, cancer and diabetes. That dangerous combination impacts key mechanisms by which both the lung and liver perform metabolism. For example, the body's ability to metabolize prescription drugs may be altered in ways that could make standard dosages too high or too low to be effective in obese people who are exposed to tobacco smoke", lead researcher Aaron Wright said.



Source: Medindia
Advertisement

Advertisement
Advertisement

Recommended Readings

Latest Obesity News

 Diabesity: Discovering the Connecting Link Between Obesity and Diabetes
Researchers examine the role of unknown protein NOTCH2-associated receptor2 (MINAR2) in obesity and diabetes using generated Minar2 knockout (KO) mice.
Beyond the Scalpel: Study Debunks Weight Loss Expectations Post Surgery
Study reports that body contouring after bariatric surgery does not contribute to long-term weight loss in patients with massive weight loss.
Revamping Weight Loss Solutions Using Anti-Obesity Medication
Recently FDA-approved drug semaglutide has proven as a highly effective anti-obesity medication showcasing remarkable weight loss benefits.
Exploring Microbiota's Influence on Weight Development
Gut bacteria profile and abundance in toddlers can serve as a predictive factor for their body mass index (BMI) at age 5, irrespective of premature birth status.
What Are the Consequences of Uncontrolled Hunger in Teenagers Living With Obesity?
Obese individuals were found to have weaker appetite regulation, with factors that inhibit eating behavior.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Combination of Smoking and Obesity is Very Dangerous Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests