By analyzing the genetic material (DNA), scientists can predict whether a person can expect to live longer or die sooner than average.
The team has analysed the combined effect of genetic variations that influence lifespan to produce a scoring system.
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‘The DNA sites with the greatest impact on overall lifespan were those that have previously been linked to fatal illnesses, including heart disease and smoking-related conditions.’
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People who score in the top ten percent of the population might expect to live up to five years longer than those who score in the lowest ten percent, they say.
The findings also revealed fresh insights into diseases and the biological mechanisms involved in ageing, the researchers say.
Experts at the University of Edinburgh's Usher Institute looked at genetic data from more than half a million people alongside records of their parents' lifespan.
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There are several myths associated with ageing and one such myth doing the rounds is that pain is a part of growing old. Is there a grain of truth in this? To find out, participate in this quiz.
Some 12 areas of the human genome were pinpointed as having a significant impact on lifespan, including five sites that have not been reported before.
Genes that have been linked to other cancers, not directly associated with smoking, did not show up in this study, however.
This suggests that susceptibility to death caused by these cancers is either a result of rarer genetic differences in affected people, or social and environmental factors.
The researchers had hoped to discover genes that directly influence how quickly people age. They say that if such genes exist, their effects were too small to be detected in this study.
The research, published in the journal eLife, was funded by the UK Medical Research Council and the AXA Research Fund.
Dr Peter Joshi, an AXA Fellow at the University of Edinburgh's Usher Institute, said: "If we take 100 people at birth, or later, and use our lifespan score to divide them into ten groups, the top group will live five years longer than the bottom on average."
Paul Timmers, PhD student at the Usher Institute, said "We found genes that affect the brain and the heart are responsible for most of the variation in lifespan."
Source: Eurekalert
Experts at the University of Edinburgh's Usher Institute looked at genetic data from more than half a million people alongside records of their parents' lifespan.
Quiz on Ageing
There are several myths associated with ageing and one such myth doing the rounds is that pain is a part of growing old. Is there a grain of truth in this? To find out, participate in this quiz.
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Some 12 areas of the human genome were pinpointed as having a significant impact on lifespan, including five sites that have not been reported before.
Genes that have been linked to other cancers, not directly associated with smoking, did not show up in this study, however.
This suggests that susceptibility to death caused by these cancers is either a result of rarer genetic differences in affected people, or social and environmental factors.
The researchers had hoped to discover genes that directly influence how quickly people age. They say that if such genes exist, their effects were too small to be detected in this study.
The research, published in the journal eLife, was funded by the UK Medical Research Council and the AXA Research Fund.
Dr Peter Joshi, an AXA Fellow at the University of Edinburgh's Usher Institute, said: "If we take 100 people at birth, or later, and use our lifespan score to divide them into ten groups, the top group will live five years longer than the bottom on average."
Paul Timmers, PhD student at the Usher Institute, said "We found genes that affect the brain and the heart are responsible for most of the variation in lifespan."
Source: Eurekalert
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We all wish to live a long and fruitful life. The life expectancy calculator may just be what the doctor ordered for those curious to know their life expectancy.
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