About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Chinese Herbal Decoction Ameliorates Insulin Resistance in Diabetic Rats

by Kathy Jones on March 18, 2011 at 8:26 PM
Font : A-A+

 Chinese Herbal Decoction Ameliorates Insulin Resistance in Diabetic Rats

The effect of the Chinese herbal decoction, Yi-Qi-Zeng-Min-Tang (YQZMT), on insulin resistance in type 2 diabetic rats has been investigated by scientists.

The prevalence of type 2 diabetes is dramatically increasing throughout the world. Insulin resistance is a hallmark of type 2 diabetes, and it most often precedes the onset of hyperglycemia and predicts development of type 2 diabetes.

Advertisement

At present, thiazolidinediones (TZD), the agonists of the peroxisome proliferators-activated receptor ?, are the main agents to improve insulin sensitivity in the liver, adipose tissue, and skeletal muscle, thus improving glycaemic control in patients with type 2 diabetes.

Despite the efficacy, some deleterious side effects of TZDs, including rosiglitazone and pioglitazone, have been noted, such as increasing body weight and aggravating heart failure through fluid retention.
Advertisement

Therefore, development of new agents may be helpful in the treatment of type 2 diabetic patients with insulin resistance.

A new research, led by Professor Wen-Jian Wang from Institute of Chinese Integrative Medicine, Huashan Hospital of Fudan University, addresses this question.

The results of this study indicated that YQZMT has beneficial effect in insulin resistance, glycaemic control, dyslipidemia, free fatty acids and adipocytokines, and does not cause any increase in body weight in high-fat diet and low-dose streptozotocin induced type 2 diabetic rats.

The findings demonstrate that YQZMT displays the insulin sensitization characteristic of rosiglitazone, but unlike rosiglitazone, does not cause any increase in body weight.

Administration of YQZMT may be a suitable adjunct for the treatment of insulin resistance patients. Further studies will be required to identify the ingredients and chemicals in YQZMT responsible for the beneficial effects observed in the present study.

The study was published on February 28, 2011 in the World Journal of Gastroenterology.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Test  Your Knowledge on Heart
Test Your Knowlege on Genes
Obesity in Teens Make Inroads into Early Atrial Fibrillation
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Diabetes - Essentials Diabetes - Self-Monitoring of Blood Glucose (SMBG) Insulin Delivery Devices Diabetes and Exercise Saint Johns Wort Metabolic Syndrome Gestational diabetes Pregnancy and Complications Type 2 Diabetes Decoding HbA1c Test for Blood Sugar 

Most Popular on Medindia

Diaphragmatic Hernia Sanatogen Selfie Addiction Calculator Sinopril (2mg) (Lacidipine) Blood - Sugar Chart Hearing Loss Calculator Blood Pressure Calculator Blood Donation - Recipients Color Blindness Calculator Loram (2 mg) (Lorazepam)
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Chinese Herbal Decoction Ameliorates Insulin Resistance in Diabetic Rats Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests