About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Cells During Embryonic Development also Rust

by Bidita Debnath on October 27, 2016 at 2:24 AM
Font : A-A+

 Cells During Embryonic Development also Rust

Oxidation is a process by which oxygen in the air cause damaging rust on cars. Similarly, a research group at Lund University in Sweden, has now identified that certain cells during embryonic development also are negatively affected by oxidation.

This oxidation is capable of leading to a block in cellular function. The researchers use a laboratory based culture system to generate new blood from pluripotent stem cells. They hope in the future to be able to use the system to generate new blood cells, including blood stem cells, for patients in need of bone marrow transplants.

Advertisement


However, laboratories worldwide attempting to generate laboratory derived blood cells, find these cells do not perform as well as blood cells from donor sources. The cells appear normal but do not grow and expand as well.

When investigating why the derived blood cells did not function as well as donor blood cells, the Lund University researchers found high levels of reactive oxygen species (a class of molecules that cause oxidation) in the newly derived blood cells. The levels were high enough to damage the cells and cause them not to grow in culture. The researchers have also developed a cocktail of factors that could reduce oxidative damage in the cells, and when used resulted in over twenty times more newly generated blood stem cells that could grow.
Advertisement

"By identifying the negative role of oxidation in new blood cells derived from pluripotent stem cells, we have identified what is perhaps the most significant hurdle in developing laboratory derived blood stem cells for transplantation based therapies.", says Niels-Bjarne Woods, who is leading the study.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Diet and Oral Health: The Sugary Connection May Become Sour
World AIDS Day 2022 - Equalize!
Test Your Knowledge on Sugar Intake and Oral Health
View all
News Archive
Date
Category
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Parkinsons Disease Surgical Treatment 

Most Popular on Medindia

Blood Donation - Recipients Nutam (400mg) (Piracetam) Diaphragmatic Hernia Color Blindness Calculator Drug Interaction Checker Turmeric Powder - Health Benefits, Uses & Side Effects Sanatogen Pregnancy Confirmation Calculator Selfie Addiction Calculator Find a Doctor
open close
ASK A DOCTOR ONLINE

×

Cells During Embryonic Development also Rust Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests