Engineered �Mini� CRISPR Genome Editing System Developed
An engineered mini version of CRISPR genome editing system has been developed by researchers. CRISPR can be as simple as a cutter, or more advanced as a regulator, an editor.
An engineered mini version of CRISPR genome editing system has been developed by researchers. CRISPR can be as simple as a cutter, or more advanced as a regulator, an editor.
‘Cells lining the blood vessel walls can now be edited for the first time using genome editing, serving as a potential application to treat various diseases like acute respiratory distress syndrome from severe COVID-19.
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The team developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which are cells that line blood vessel walls. “With this nanoparticle we can introduce genes to inhibit vascular injury and/or promote vascular repair, correct gene mutations and turn genes on or off to restore normal function. It also allows us to edit multiple genes at the same time. This is an important advance for treating any disease caused by endothelial dysfunction,” says senior author Dr. Youyang Zhao, PhD, from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago.
Source-Medindia
Patent Law can Stop Unethical Human-Genome Editing
Patent law could create an ethical thicket around human genome editing, as it has great potential. The World Health Organization (WHO) says that countries should develop their own regulations and follow them strictly.
Patent law could create an ethical thicket around human genome editing, as it has great potential. The World Health Organization (WHO) says that countries should develop their own regulations and follow them strictly.
Phenylketonuria, the Genetic Disease Healed Using Genome Editing
Phenylketonuria, a birth defect that increases the levels of a substance called phenylalanine in the blood is healed using CRISPR/Cas9 system.
Phenylketonuria, a birth defect that increases the levels of a substance called phenylalanine in the blood is healed using CRISPR/Cas9 system.
Genome Editing reduces Cholesterol in Large Animal Model
Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey.
Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey.
