Medindia LOGIN REGISTER
Medindia
Advertisement

Breast Irradiation Guidelines Updated

by Anjali Aryamvally on October 28, 2017 at 3:32 PM
Breast Irradiation Guidelines Updated

Appropriate and safe utilization of accelerated partial-breast irradiation (APBI) guidelines were updated and published online in the journal, Brachytherapy. It was led by Cleveland Clinic researcher Chirag Shah, M.D.

APBI is a breast radiation therapy technique in which targeted radiation is delivered, either via brachytherapy (applicator devices or multiple catheters) or through external radiation, specifically to the part of the breast where the tumor was removed without treating the whole breast.

Advertisement


For patients with ductal carcinoma in situ (DCIS) and early-stage invasive breast cancer, APBI has been shown to be an alternative to standard whole-breast irradiation, allowing for a reduction in the duration of radiation therapy. The technique, by reducing the amount of normal healthy breast tissue treated with radiation, may also reduce side effects of treatment and improve cosmetic outcomes.

In updating the guidelines, Dr. Shah led a group of physicians - appointed by the American Brachytherapy Society, with expertise in breast cancer and breast brachytherapy - to develop a consensus statement. The new guidelines recommend the technique for a broader group of patient by allowing younger patients to be eligible as well as those with DCIS. The authors' consensus is that the appropriate candidates for APBI include patients aged 45 years or older; all invasive histologies and ductal carcinoma in situ; tumors 3 cm or less; node negative; estrogen receptor positive/negative; no lymphovascular space invasion; and negative margins.
Advertisement

"The updated guidelines support clinicians by offering them the ability to appropriately select patients for APBI, and data that supports the techniques," said Dr. Shah. "Guidelines allow for the selection of patients who can finish radiation treatment in one week or less, compared to the traditional period of three to six weeks, and potentially a reduction in side effects depending on the APBI technique."

The previous APBI guidelines, also led by Dr. Shah, were developed in 2013. Since then, multiple randomized trials have been published which have increased the amount of data available to develop the updated guidelines. The authors' recommendation was based on review of literature including randomized trials, prospective studies, multi-institutional series, and single-institution reports addressing clinical outcomes and toxicities with APBI.



Source: Eurekalert
Font : A-A+

Advertisement

Advertisement
Advertisement

Recommended Readings

Latest Women Health News

AI Tool Precisely Detects Postpartum Hemorrhage
An AI tool called Flan-T5 identified postpartum hemorrhage with 95% precision and detected 47% patients with the condition.
Active Scrutiny of Cervical Lesions Fuels Long-Term Cervical Cancer Risk
Active surveillance of cervical lesions was associated with higher cervical cancer risk in the long term compared to its removal.
Contraceptive Pills To Go Over-the-Counter Sale in Japan
Japan initiated the trial of selling morning-after contraceptive tablets over-the-counter in an effort to lower abortion rates and solace for rape victims.
Urinary Tract Infections Surge in Indian Women Due to Ignorance
The rising number of urinary tract infections (UTIs) among Indian women can be attributed primarily to social stigma and a lack of awareness.
Auto-Immune Disease of Pregnancy Linked to Fetal Heart Disorders
Pregnant women with Sjogren's or lupus syndrome have elevated anti-Ro/SSA antibodies which are linked to fetal atrioventricular block in the heart.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Breast Irradiation Guidelines Updated Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests