About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Breakthrough in the Management of Severe Acute Pancreatitis

by Medindia Content Team on October 13, 2007 at 8:48 PM
Font : A-A+

Breakthrough in the Management of Severe Acute Pancreatitis

From meta-analysis based on current available clinical studies early nasogastric enteral nutrition appeared effective and safe in clinical practice.

Three randomized controlled clinical trials were eligible, and 131 participants were included. Of them, 67 were randomly assigned to the early nasogastric enteral nutrition group and 64 to the conventional nutritional route group. Conventional routes included total parenteral nutrition and nasojejunal enteral nutrition.

Advertisement

Nutritional management of severe acute pancreatitis is regarded as an indispensable approach. Total parenteral nutrition and gastrointestinal tract rest have been recommended in the management of severe acute pancreatitis since the mid 1990s.

Some studies have attempted to assess the feasibility and safety of early enteral nutrition through nasogastric route.

Early nasogastric enteral nutrition is a breakthrough in the management of severe acute pancreatitis. Previously, it was forbidden because it might potentially oppose the requirement of pancreatic rest in the acute inflammation phase. However, the present systematic review of three randomized controlled trials showed that nasogastric route does not worsen the clinical outcomes compared with the conventional total parenteral or jejunal enteral routes.
Advertisement

Gastrointestinal and pancreatic rest has been regarded as an important factor for management of severe acute pancreatitis. Nevertheless, nasogastric enteral nutrition disobeys this discipline. Whether the nasogastric route is able to gain similar results to gastrointestinal and pancreatic rest needs to be further investigated. If possible, serological, radiological or histological appraisal should be considered for the effectiveness and safety of early nasogastric enteral nutrition in the treatment of severe acute pancreatitis.

Nasogastric route is much more convenient in clinical practice. Moreover, it is obviously cheaper than nasojejunal tube placement. Based on the present results, nasogastric enteral nutrition can be applied in the early management of severe acute pancreatitis. However, before its application in clinical practice, further investigation is necessary to validate its effectiveness and safety.

The research group evaluated the effectiveness and safety of early nasogastric enteral nutrition for severe acute pancreatitis compared with conventional nutritional routes. Based on current studies, early nasogastric enteral nutrition appears effective and safe, but the available evidence is limited.

Source: Eurekalert
SPH/C
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Pancreatitis 
Recommended Reading
Pancreatitis
Pancreatitis or inflammation of the pancreas may show up as acute pancreatitis or chronic pain. Alco...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use