Now a new study states the lack of common ground in this area reflects the fact that people with autism have connections that are uniquely their own.
According to the scientists, the research could help lead to better diagnosis of autism and improve treatments.
The scientists studied data taken from functional magnetic resonance imaging (fMRI).
"Resting-state brain studies are important because that is when patterns emerge spontaneously, allowing us to see how various brain areas naturally connect and synchronise their activity," said Avital Hahamy, a Ph.D. student in Dr Weizmann's Neurobiology Department.
The control participants' brains had similar connectivity patterns across different individuals. However, those with autism tended to display much more unique patterns.
Differences between the patterns in the autism and control groups could be explained by the way individuals in the two groups communicate with their environment.
Mr Hahamy said, "From a young age, the average, typical person's brain networks get moulded by intensive interaction with people and the mutual environmental factors."
Such shared experiences could tend to make the synchronisation patterns in the control group's resting brains more similar to each other.
It is possible that in ASD, as interactions with the environment are disrupted, each one develops a more uniquely individualistic brain organisation pattern.
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