About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Brain Tumors Could Be Fought By Immune System: Researchers

by Rukmani Krishna on June 1, 2013 at 11:36 PM
Font : A-A+

 Brain Tumors Could Be Fought By Immune System: Researchers

One of the most serious types of brain tumour, glioblastoma multiforme, could be fought by the patients' own immune system, according to research at Lund University in Sweden. The tumours are difficult to remove with surgery because the tumour cells grow into the surrounding healthy brain tissue. A patient with the disease therefore does not usually survive much longer than a year after the discovery of the tumour.

The team has tested different ways of stimulating the immune system, suppressed by the tumour, with a 'vaccine'. The vaccine is based on tumour cells that have been genetically modified to start producing substances that activate the immune system. The modified tumour cells (irradiated so that they cannot divide and spread the disease) have been combined with other substances that form part of the body's immune system.

Advertisement

The treatment has produced good results in animal experiments: 75 per cent of the rats that received the treatment were completely cured of their brain tumours. "Human biology is more complicated, so we perhaps cannot expect such good results in patients. However, bearing in mind the poor prognosis patients receive today, all progress is important", said doctoral student Sara Fritzell, part of the research group led by consultant Peter Siesjö.

She has previously tested combining the activation of the immune system with chemotherapy. When the chemotherapy was applied directly to the tumour site, the positive effects reinforced each other, and a huge 83 per cent of the mice survived."Our idea is in the future to give patients chemotherapy locally in conjunction with the operation to remove as much of the tumour as possible", said Sara Fritzell.

Peter Siesjö is currently applying for permission to carry out a clinical study on stimulation of the immune system - with or without local chemotherapy - as a treatment for patients with glioblastoma multiforme.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Black Pepper as Preventive Measure Against Omicron
FODMAP Diet: A Beginner's Guide
Smallpox
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Parkinsons Disease Parkinsons Disease Surgical Treatment Brain Tumor Brain Tumors Brain Brain Facts Ataxia Myasthenia Gravis Language Areas in The Brain Ways to Improve your Intelligence Quotient (IQ) 

Recommended Reading
Brain Tumor
Brain tumors are the abnormal growth of brain cells that may be benign or metastatic. Brain tumors ....
Headache / Cephalgia
A headache literally means 'pain in the head'. It is a common complaint that may occur frequently .....
New Mutations Associated With Majority of Brain Tumor Subtype Identified
Mutations responsible for more than half of a subtype of lethal childhood brain tumor have been ......
Ataxia
Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or ...
Language Areas in The Brain
The mechanism of how human brain processes the language to express and comprehend the verbal, writte...
Myasthenia Gravis
Myasthenia gravis is the commonest disorder of neuromuscular transmission. Autoimmune myasthenia gra...
Parkinsons Disease
Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Ways to Improve your Intelligence Quotient (IQ)
Intelligence quotient (IQ) is a psychological measure of human intelligence. Regular physical and me...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use