About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Brain Damage Among Critically Ill Children as High as 16%

by Dr. Meenakshy Varier on April 17, 2017 at 4:15 PM
Font : A-A+

Brain Damage Among Critically Ill Children as High as 16%

Acute neurological conditions with brain damage are a common health problem in children admitted to pediatric intensive care units (ICUs). About 16% of these children have acute neurological conditions due to cardiac arrest, traumatic brain injury, or other causes, according to an international survey study in Pediatric Critical Care Medicine. The journal is published by Wolters Kluwer.

"Children with acute neurologic insults are common in ICUs and are associated with high morbidity and mortality rates and prolonged ICU stays, posing significant challenges to public, family, and individual health," according to the report by the PANGEA Investigators, led by Ericka L. Fink, MD, MS, of Children's Hospital of Pittsburgh. The findings underscore the need for "transformational ideas" to improve outcomes for this large group of critically ill children at high risk of adverse clinical outcomes.

Advertisement


Worldwide Snapshot of Acute Neurological Conditions Among Critically Ill Children The PANGEA study (Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment) was designed to assess the multinational prevalence and outcomes of critical neurological injuries and illnesses among children in participating ICUs. On four days during a one-year period, ICUs at 107 hospitals provided information on children with acute neurological conditions.

"Acute neurological conditions in children are associated with high mortality and morbidity (cognitive, physical and emotional disability) rates, and largely lack targeted neuroprotective therapies that improve outcome," Dr. Fink explains. "Measuring the burden of these conditions is a step towards strategizing prospective study design and allocation of resources to achieve the long-term goal of improving outcome for these children."
Advertisement

The hospitals contributed information on a total of 924 patients. Although nearly 90% of the hospitals were in North America or Europe, hospitals in Africa, Asia, Oceania and South America were represented as well. A separate study looking specifically at traumatic brain injury at low-resource settings in Africa is underway (PANGEA-Developing Countries). Overall, 16.2% of children in the reporting ICUs had acute neurological conditions. The children's ages ranged from seven days to 17 years. Many children had preexisting medical conditions, but 61% had normal neurological status before their current hospitalizations.

Cardiac arrest, resulting in lack of blood flow to the brain, was the most common overall cause of acute neurological conditions (23%). Other causes included traumatic brain injury (19%), central nervous system infection or inflammation (16%), and stroke or a mass, such as a brain tumor (9% each).

Regions differed in terms of most common condition reported. Infection/inflammation was the most common cause in Asia, South America, and the sole African hospital contributing to the study. In all other regions, cardiac arrest was the main cause.

The children were at high risk of poor outcomes. Twelve percent died overall, the highest rate in children with cardiac arrest (24%). Another 32% were left with moderate to severe neurological disability at the three-month follow-up, including nearly half of those with traumatic brain injury. The children had long lengths of stay, an average of 13 days in the ICU and 22 days in the hospital.

"The growth of pediatric neurocritical care services in pediatric ICUs and development of a pediatric neurocritical care research network reflect the specialty's acknowledgment and commitment to improve outcomes for children with acute neurologic insults," Dr. Fink and coauthors write. They believe that the PANGEA data "suggest a vital need for resources to assist in the challenge of improving outcomes for these children throughout the span of the periods of emergency care through to rehabilitation."



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
Long-Term Glycemic Control - A Better Measure of COVID-19 Severity
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Coma Parkinsons Disease Parkinsons Disease Surgical Treatment Height and Weight-Kids Brain Brain Facts Ataxia Language Areas in The Brain Ways to Improve your Intelligence Quotient (IQ) 13 Daily Habits that Damage the Brain 

Recommended Reading
Coma
Coma is a deep state of unconsciousness where the affected individual is alive but is not able to .....
Zika Infection During Pregnancy can Cause Miscarriages and Lead to Brain Damage in Infants
Study states that having an intact immune systems cannot offer protection against Zika infection ......
Proofs Concerning Zika Virus Link to Brain Damage
Two reports show the evidence of Zika Virus disease in the neural tissue of affected infants in ......
Anti-Inflammatory Drug That Limits, Repairs Brain Damage in Stroke Patients
A new drug that can potentially reduce the number of brain cells destroyed by stroke as well as ......
13 Daily Habits that Damage the Brain
The brain is probably the most important organ in our body and it deserves special care and attentio...
Ataxia
Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or ...
Language Areas in The Brain
The mechanism of how human brain processes the language to express and comprehend the verbal, writte...
Parkinsons Disease
Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Ways to Improve your Intelligence Quotient (IQ)
Intelligence quotient (IQ) is a psychological measure of human intelligence. Regular physical and me...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use