With treatment there was complete normalization of cortical gray matter thickness in the long-term weight rehabilitated anorexia nervosa patients.
Researchers have found that changes in brain structure - global
thinning of cortical gray matter - in acutely ill anorexia nervosa patients can
be completely reversed with successful weight rehabilitation therapy.
The study participants were subjected to MRI scanning
immediately following admission to specialized eating disorder clinics at the Dresdener
University Hospital. Thereafter, they were treated successful with complete
restoration of normal weight, eating behavior and menstruation. It was noticed
that roughly 50 percent of the patients who received treatment successfully
maintain these criteria. Prof. Stefan Ehrlich explained, "We observed
complete normalization of cortical gray matter thickness in the long-term
weight rehabilitated patients in our sample. Not only the spatial expanse but
also the magnitude of cortical gray matter thinning in acute anorexia nervosa
is noteworthy - comparable to that typically observed in Alzheimer's
disease."
Though it is an encouraging finding for those suffering from
the eating disorder, it is an extremely long road to long-term recovery, and anorexia
nervosa may have other serious long-term consequences that are not reversible,
such as reduction of bone mass due to osteoporosis.
The findings are published in the renowned journal Biological
Psychiatry.
Source-Medindia