Levels of bisphenol A (BPA) in components of dialysis machines may be toxic to the immune cells circulating in patients' blood suffering from kidney failure.
This is according to a study that will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.
The hormone disruptor BPA is found in various components of dialysis machines—or dialyzers—that filter kidney failure patients' blood. Researchers led by Mauro Neri (San Bortolo Hospital, in Italy) analyzed the amount of BPA released by three different types of dialyzers and the effects of the released BPA on immune cells found in the blood.
Elisio 17H released less BPA than the other dialyzers. Also, the viability was higher, while necrosis and cell death were lower in immune cells incubated in media circulated through this type of dialyzer.
"Use of alternative polymers for dialyzers' components may reduce BPA elution during dialysis. However, more experiments are needed to confirm these results," the investigators wrote.