Bisphenol A (BPA) exposure may put females at greater risk of damage from stress as compared to males, reveals a new study.
The study from a University of Cincinnati (UC) found that heart function and blood pressure in mice exposed to BPA from birth though young adulthood are affected differently in males and females.
Bisphenol A Poses No Health Risk
The EU food safety watchdog said that bisphenol A --a chemical used in food can linings and other products-- poses no health risk to consumers.
Advertisement
Researchers found that in young BPA exposed female mice, the heart is more sensitive to stress-induced ischemic damage in a way not observed in untreated female mice.
Researcher Scott Belcher said that in BPA-exposed female mice, isoproterenol, a drug that leads to hypertrophy (tissue enlargement) by mimicking some effects of a heart attack, caused increased heart muscle damage along with accumulation of collagen, an indicator of fibrosis or scarring, in the heart.
![Bisphenol A Substitutes are Dangerous: Study]( "Bisphenol A Substitutes are Dangerous: Study")
Bisphenol A is a plastic ingredient banned in some countries over the health fears. Two of the substitutes used for bisphenol are also a source of concern, French researchers warned Thursday.
In male mice BPA alone increased fibrosis, however researchers did not observe an additional increase in fibrosis, ischemic damage, or hypertrophy in response to isoproterenol treatments.
BPA, an environmental pollutant with estrogen-like activity, is used to make polycarbonate plastic and epoxy resins and is a common contaminant of many packaged foods and beverages. Numerous studies have linked BPA to neurological defects, diabetes and breast and prostate cancer.
Belcher added that the results of this study find heart and blood pressure effects in male and female mice, with females seemingly at greater risk for harm. They used an isoproterenol model that in some ways mimics damage that can occur during a heart attack. For female mice exposed to BPA there was a severe increase in the sensitivity to cardiotoxic damage. This effect was especially striking because females are typically protected.
The findings are published online in the journal Endocrinology.
Source: ANI
Bisphenol A Substitutes are Dangerous: Study
Bisphenol A is a plastic ingredient banned in some countries over the health fears. Two of the substitutes used for bisphenol are also a source of concern, French researchers warned Thursday.
Advertisement
In male mice BPA alone increased fibrosis, however researchers did not observe an additional increase in fibrosis, ischemic damage, or hypertrophy in response to isoproterenol treatments.
BPA, an environmental pollutant with estrogen-like activity, is used to make polycarbonate plastic and epoxy resins and is a common contaminant of many packaged foods and beverages. Numerous studies have linked BPA to neurological defects, diabetes and breast and prostate cancer.
Belcher added that the results of this study find heart and blood pressure effects in male and female mice, with females seemingly at greater risk for harm. They used an isoproterenol model that in some ways mimics damage that can occur during a heart attack. For female mice exposed to BPA there was a severe increase in the sensitivity to cardiotoxic damage. This effect was especially striking because females are typically protected.
The findings are published online in the journal Endocrinology.
Source: ANI
Bisphenol A Health Threats Raise Concerns
The exposure levels to Bisphenol A, which is a health concern for babies, should be cut by a factor of 10, according to the EU food safety watchdog
Advertisement
Exposure to Bisphenol A Could Lead to MiscarriageExposure to bisphenol A - a chemical found in plastic could increase the risk of miscarriage, says study. | Advertisement
|
Advertisement
Latest Research News
Link between advanced paternal age and higher risks for reproductive and offspring medical problems has been discovered.
Can gene astrology predict disease risk? Yes, your genes can determine your future health and disease risk.
Injury to the white matter explains why football players are at an increased risk for cognitive and behavioral problems later in life.
Located at the South Col, the rocky area between Mount Everest and Lhotse serves as the final campsite for climbers as well as a frozen legacy of hardy microbes.
The new finding is found to be valuable for screening specific medications and treatment against Giardia and other protozoan parasites.