The wrinkle-smoother worked very well in its Phase III
clinical trials, where it demonstrated significantly greater decrease in
headache days among patients receiving it as compared with those receiving a
The company said that injections of Botox at sites like
forehead, temples and potentially extending into the neck muscles were well
tolerated by patients.
It is estimated that 1.2 million to 3.6 million people in
the United States suffer from chronic migraine.