A researcher has identified a new pathway used by the malaria parasite to infect human cells.
The discovery, by researchers at The Walter and Eliza Hall Institute, provides a new vaccine target through which infection with the deadly disease could be prevented.
Malaria - Waterborne
Encyclopedia section of medindia gives general information about About Malaria Causes
Advertisement
The most lethal form of malaria is caused by the parasite Plasmodium falciparum.
For decades, it has been known that malaria parasites use proteins called glycophorins as a means of entering red blood cells.
This new research reveals an alternative pathway used by the parasite to enter red blood cells.
![Mosquito Diseases]( "Mosquito Diseases")
Mosquito-borne diseases, like malaria, filaria, dengue, etc are common in places conducive of mosquito breeding. Swamps, ponds and stagnated drainage provide optimal breeding ground for mosquitoes.
The pathway does not involve glycophorins, instead requiring the binding of a parasite molecule named PfRh4 to Complement Receptor 1 (CR1), a common protein found on the surface of red blood cells.
Professor Alan Cowman Cowman said the PfRh family of surface proteins is involved in the recognition of red blood cell receptors, which allows the parasite to attach to the red blood cell surface and gain entry.
The research was published in the journal Proceedings of the National Academy of Sciences USA.
Source: ANI
This new research reveals an alternative pathway used by the parasite to enter red blood cells.
Mosquito Diseases
Mosquito-borne diseases, like malaria, filaria, dengue, etc are common in places conducive of mosquito breeding. Swamps, ponds and stagnated drainage provide optimal breeding ground for mosquitoes.
Advertisement
The pathway does not involve glycophorins, instead requiring the binding of a parasite molecule named PfRh4 to Complement Receptor 1 (CR1), a common protein found on the surface of red blood cells.
Professor Alan Cowman Cowman said the PfRh family of surface proteins is involved in the recognition of red blood cell receptors, which allows the parasite to attach to the red blood cell surface and gain entry.
The research was published in the journal Proceedings of the National Academy of Sciences USA.
Source: ANI
Malaria Parasite Migrates from Gorilla to Man
Malaria's most dangerous parasite has crossed the species barrier from gorilla to man, warned scientists.
Advertisement
 World's First In-depth Study of the Malaria Parasite Genome Completed by NTU ResearchersMore potent drugs or a vaccine for malaria could result from groundbreaking research done at Singapore's Nanyang Technological University's (NTU) School of Biological Sciences (SBS) | Advertisement
|
Advertisement
Recommended Reading
Latest Research News
Sobering truth about foot travel in the United States emerges from international statistics, highlighting the prevalence of walking on the Blacksburg campus.
Unveiling a hidden mechanism, proteins within brain cells exhibit newfound abilities at synapses, reinforcing Darwin's theory of adaptation and diversity in the natural world.
Combining micro-needling and cupping, two emerging and alternative techniques, in an experimental study reveals a potential synergy for skin rejuvenation.
Despite a decline in COVID-19 cases, the World Health Organisation (WHO) raises global concerns by warning of an "inevitable" next pandemic known as "Disease X".
According to a study, a team of Japanese researchers aims to pioneer a laboratory-based method for baby development by 2028.