Blood transfusion from pregnant women is associated with an increased risk of death among male recipients of transfusions but not among female recipients.
The most common cause of transfusion-related mortality is transfusion-related acute lung injury (TRALI), which has also been shown to be associated with transfusions from female donors. Furthermore, TRALI is associated specifically with transfusions from female donors with a history of pregnancy.
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‘Patients who received red blood cell transfusions from a female recipient who was pregnant are at an increased risk of death.’
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Rutger A. Middelburg, Ph.D., of Sanquin Research, Leiden, the Netherlands, and colleagues conducted a study of first-time transfusion recipients at six major Dutch hospitals to quantify the association between red blood cell transfusion from female donors with and without a history of pregnancy and mortality of red blood cell recipients.
The group for the primary analyses consisted of 31,118 patients who received 59,320 red blood cell transfusions from 1 of 3 types of donors (88 percent male; 6 percent ever-pregnant female; and 6 percent never-pregnant female).
![Safer Blood Transfusion Symposium in India: Highlights]( "Safer Blood Transfusion Symposium in India: Highlights")
Making blood transfusion safer in India was the focus of the symposium on Sunday that had experts from Transfusion Medicine speaking on the event organized by Jeevan Blood Bank, Chennai, India.
The number of deaths in this group was 3,969 (13 percent mortality). For male recipients of red blood cell transfusions, all-cause mortality rates after a red blood cell transfusion from an ever-pregnant female donor vs male donor were 101 vs 80 deaths per 1,000 person-years.
For receipt of transfusion from a never-pregnant female donor vs male donor, mortality rates were 78 vs 80 deaths per 1,000 person-years. Among female recipients of red blood cell transfusions, mortality rates for an ever-pregnant female donor vs male donor were 74 vs 62 per 1,000 person-years.
Source: Eurekalert
Safer Blood Transfusion Symposium in India: Highlights
Making blood transfusion safer in India was the focus of the symposium on Sunday that had experts from Transfusion Medicine speaking on the event organized by Jeevan Blood Bank, Chennai, India.
Advertisement
The number of deaths in this group was 3,969 (13 percent mortality). For male recipients of red blood cell transfusions, all-cause mortality rates after a red blood cell transfusion from an ever-pregnant female donor vs male donor were 101 vs 80 deaths per 1,000 person-years.
For receipt of transfusion from a never-pregnant female donor vs male donor, mortality rates were 78 vs 80 deaths per 1,000 person-years. Among female recipients of red blood cell transfusions, mortality rates for an ever-pregnant female donor vs male donor were 74 vs 62 per 1,000 person-years.
Source: Eurekalert
First Synthetic Blood Transfusion: A Reality by 2017
In a news release, the United Kingdom's National Health Services (NHS) announced its intention to test out lab-produced red blood cells transfusions to human volunteers in 2017.
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