About My Health Careers Internship MedBlogs Contact us

Blood Pumped by the Heart Determines Blood Flow in the Memory Center of the Brain

by Anjali Aryamvally on November 12, 2017 at 11:50 AM
Font : A-A+

Blood Pumped by the Heart Determines Blood Flow in the Memory Center of the Brain

Older adults may have reduced blood flow in the memory-processing areas of their brain if their hearts pump less blood, reports study published in Neurology, the medical journal of the American Academy of Neurology.

"Our findings show that when the heart does not pump blood as effectively, it may lead to reduced blood flow in the right and left temporal lobes, areas of the brain that process memories," said study author Angela L. Jefferson, PhD, of Vanderbilt University Medical Center in Nashville, Tenn., and member of the American Academy of Neurology. "What is surprising is the reduction we observed is comparable to brain blood flow in someone 15 to 20 years older."


For the study, researchers enrolled 314 people with an average age of 73 who did not have heart failure, stroke, or dementia. Of that group, 39 percent had mild cognitive impairment, a condition that puts a person at an increased risk of developing dementia or Alzheimer's disease.

Participants were given echocardiograms to measure cardiac index, or how much blood the heart pumped relative to body size. Blood flow in the brain was measured with magnetic resonance imaging (MRI).

Researchers found that lower cardiac index corresponded to lower blood flow in the brain. In the left temporal lobe, blood flow was lower, on average, by 2.4 milliliters of blood per 100 grams of tissue per minute for every one unit decrease in cardiac index. This amount is similar to the average decrease in blood flow that would be expected with more than 15 years of aging. In the right temporal lobe, the effect was 2.5 milliliters of blood per 100 grams of tissue per minute, equivalent to more than 20 years of aging. This was after adjusting for various factors that could affect blood flow, including mild cognitive impairment, age, education, and whether a person had the Alzheimer's APOE e4 gene.

"Our results suggest mechanisms that regulate blood flow may become more vulnerable as a person ages, even before cognitive impairment sets in," Jefferson said. "This important observation warrants further study. It is also possible the temporal lobes, where Alzheimer's disease first begins, may be especially vulnerable due to a less extensive network of sources of blood flow. If we can better understand how this process works, we could potentially develop prevention methods or treatments."

Source: Eurekalert

News A-Z
News Category
What's New on Medindia
Is COVID-19 Vaccination during Pregnancy Safe?
Sensory Processing Disorder (SPD)
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Parkinsons Disease Thalassemia Parkinsons Disease Surgical Treatment Heart Brain Healthy Heart Brain Facts Ataxia Statins Mitral Valve Prolapse 

Recommended Reading
Gold Nanoparticles to Track Blood Flow
Study proposes method for the preparation of iridium-coated gold nanoparticles as luminescent ......
Blood Flow Rescue After Injury Through 'Nano-in-micro' Stem Cell Delivery
Cells are deprived of oxygen and nutrients,when blood flow is reduced or cut to tissues, which can ....
Ovarian Cancer: CT Technology Shows How Blood Flow Can Predict Treatment Effectiveness?
CT technology can show how blood flow could predict the treatment effectiveness of ovarian cancer....
Stuttering Linked to Less Blood Flow in the Brain Region Associated With Language
Disturbances in the speech processing areas of the brain are likely of central importance as a ......
Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or ...
Mitral Valve Prolapse
Mitral Valve Prolapse is a relatively common condition and causes leakage of blood through the valve...
Parkinsons Disease
Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Statins are new wonder drugs that are proving to be efficacious, not merely in relieving symptoms bu...
Thalassemia is an inherited blood disorder passed on through parental genes causing the body to prod...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use