About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Bitter Taste Receptor Gene Activates An Immune Response

by Bidita Debnath on October 13, 2012 at 10:36 PM
Font : A-A+

 Bitter Taste Receptor Gene Activates An Immune Response

Researchers say that, people who find some vegetables like sprouts and broccoli unbearably bitter are better at fighting off bugs due to chemicals in their nose.

Experiments found that such people have more receptors that pick up the flavour of these foods and also work as an early warning system about bacterial invaders.

Advertisement

The researchers found that hating sprouts could actually mean you get ill less often and said that a third of people have a 'supertaster' gene that makes sprouts taste bitter - but mean they can fight infection.

They were traditionally thought to be located only on the tongue but are now known to be in the linings of the nasal and sinus cavities as well.
Advertisement

These receptors are also involved in activating the body's natural defence against common infections.

However, almost a third of the population do not have the specific version of the bitter taste receptor gene called TAS2R38 that activates an immune response.

"If you are a supertaster, it is going to be very rare you are going to get sinusitis," the Daily Mail quoted Dr Noam Cohen from the University of Pennsylvania in the United States as saying.

However, he added that this bitter-tasting ability does not protect against all infections.

For the study, the researchers grew cells in lab dishes, forming structures that resembled the multilayered lining of the nose and sinus, to test out how bitter receptors affect the initial stages of the infection process.

Chemicals produced by common bacteria called Pseudomonas aeruginosa activated the TAS2R38 bitter receptor, and caused the hair-like cilia that line the sinuses to start sweeping away microbial intruders.

The activation also resulted in the release into the sinuses of nitric oxide which kills bacteria.

The researchers looked at just one of 25 bitter receptors and it remains to be seen if the others affect the immune system.

The study also suggests that supertasters may have a higher risk of chronic sinusitis, and that non-tasters have more upper respiratory infections.

Upon testing nasal tissue samples from patients who had undergone surgery related to sinus problems, the researchers found none of the eleven supertasters had Pseudomonas bacteria in their tissues, whereas seven out of twenty non-tasters had infections.

The study has been published in the Journal of Clinical Investigation.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Top 10 Vitamin B12 Foods for Vegetarians - Slideshow
Targeted Screening Program Beneficial for Prostate Cancer Screening
Are Menopause Symptoms Troubling You?: Try these Options
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
DNA Finger Printing Myasthenia Gravis Weaver Syndrome 

Most Popular on Medindia

Blood Pressure Calculator Noscaphene (Noscapine) A-Z Drug Brands in India Drug Interaction Checker Calculate Ideal Weight for Infants Blood - Sugar Chart Hearing Loss Calculator Color Blindness Calculator Sinopril (2mg) (Lacidipine) Vent Forte (Theophylline)

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use