A new study has found that aspirin might help protect men's hearts far better than those of the fairer sex.
The new study from the James Hogg iCapture Centre for Cardiovascular and Pulmonary Research has highlighted the influence of gender on aspirin's protective powers.
Heart Attack
Heart attack is the death of the heart muscle due to loss of blood supply. Heart disease is the leading cause of death in the United States. Other names for heart attack include acute myocardial infarction, coronary thrombosis, and coronary occlusion.
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For the study, the research team examined the results of 23 previously published clinical trials for the effect for aspirin in heart attack prevention, involving more than 113,000 patients.
The authors then analysed how much the ratio of men to women in these trials affected the trials' outcomes.
"Trials that recruited predominantly men demonstrated the largest risk reduction in non-fatal heart attacks," Dr Don Sin, co-author of the study, said.
![Job Strain Doubles the Risk of Another Heart Attack]( "Job Strain Doubles the Risk of Another Heart Attack")
A stressful job is especially harmful for people who have experienced a stroke, for a new study by researchers from University Laval's Faculty of Medicine
"The trials that contained predominately women failed to demonstrate a significant risk reduction in these non-fatal events. We found that a lot of the variability in these trials seems to be due to the gender ratios, supporting the theory that women may be less responsive to aspirin than men for heart protection," Dr Sin added.
The mechanisms of this resistance are not yet understood, although recent studies have shown that men and women have major differences in the structure and physiology of the heart's blood vessels.
"From our findings we would caution clinicians on the prescribing aspirin to women, especially for primary prevention of heart attacks," Dr Sin said.
"Whether or not other pharmaceutical products would be more effective for women is unclear; more sex-specific studies should now be conducted," Dr Sin added.
The latest study is published in the online open access journal BMC Medicine.
Source: ANI
SRM /J
"Trials that recruited predominantly men demonstrated the largest risk reduction in non-fatal heart attacks," Dr Don Sin, co-author of the study, said.
Job Strain Doubles the Risk of Another Heart Attack
A stressful job is especially harmful for people who have experienced a stroke, for a new study by researchers from University Laval's Faculty of Medicine
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"The trials that contained predominately women failed to demonstrate a significant risk reduction in these non-fatal events. We found that a lot of the variability in these trials seems to be due to the gender ratios, supporting the theory that women may be less responsive to aspirin than men for heart protection," Dr Sin added.
The mechanisms of this resistance are not yet understood, although recent studies have shown that men and women have major differences in the structure and physiology of the heart's blood vessels.
"From our findings we would caution clinicians on the prescribing aspirin to women, especially for primary prevention of heart attacks," Dr Sin said.
"Whether or not other pharmaceutical products would be more effective for women is unclear; more sex-specific studies should now be conducted," Dr Sin added.
The latest study is published in the online open access journal BMC Medicine.
Source: ANI
SRM /J
Aspirin-like Compound Triggers Immune Response in Plants
Researchers at the Boyce Thompson Institute for Plant Research (BTI) have found that an aspirin-like compound is what triggers the immune response in plants.
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