Researchers find that perinatal outcomes of frozen/thawed embryo replacement (FER) have better outcomes compared to fresh in vitro fertilization (IVF).

"FER is used increasingly in IVF programs to avoid the risks associated with multiple births," said Ulla-Britt Wennerholm, of Sahlgrenska University Hospital in Göteberg, Sweden. "We sought to analyze the outcomes compared to spontaneous conceptions and fresh IVF."
Dr. Wennerholm and her associates found children born after FER had higher rates of PTB, very PTB, LBW, very LBW, LGA, and macrosomia compared to spontaneous conceptions. However, when compared to fresh IVF births, children born after FER fared better, having lower rates of PTB, LBW, and SGA. But they also found children born after FER to have higher rates of LGA and macrosomia than those born from fresh IVF.
Researchers concluded outcomes for FER to be better compared to fresh IVF, but worse compared to the general population. However, they believe the higher rates of LGA and macrosomia compared to fresh IVF will require further attention.
Source-Eurekalert