A new study reveals that using multispectral photoacoustic imaging, a combination of laser optics and ultrasound imaging technologies, can help distinguish benign and malignant prostate tissue.
Researchers at the University of Rochester looked at 42 prostatectomy specimens using the new imaging technique. Multispectral photoacoustic imaging, still in its infancy, predicted 25 out of 26 benign tissues correctly and 13 out of 16 malignant tissues correctly, said Dr. Vikram Dogra, lead author of the study.
Lipids, water, oxyhemoglobin and deoxyhemoglobin in the blood all respond to laser light, said Dr. Dogra. "By observing increases and decreases in these four things, we can tell if the tissue is malignant or benign, he said. Deoxyhemoglobin is the biggest distinguisher between malignant and benign. If deoxyhemoglobin increases even slightly in intensity, the odds that the tissue is malignant increases dramatically," he said.
Dr. Dogra will present his study at the ARRS annual meeting on April 18 in Washington, DC.