Medindia
Advertisement

Aspirin Frequent Use Linked to Increased Bleeding

by Ramya Rachamanti on January 23, 2019 at 12:25 PM
Font : A-A+

Aspirin Frequent Use Linked to Increased Bleeding

Aspirin intake on a regular basis could prevent heart attacks and strokes but leads to an increased risk of almost 50% in major bleeding episodes, according to a new study published in the Journal of the American Medical Association (JAMA).

The systematic review from scientists at King's College London and King's College Hospital looked at the overall effects on patients who did not have known cardiovascular disease. They found that while it was associated with a lower risk of heart attacks and other cardiovascular events, it did lead to an increased risk of major bleeding.

Advertisement


While aspirin is known to reduce risks for those who have previously suffered strokes and heart attacks, the evidence of the role of aspirin in the initial prevention of cardiovascular events, is uncertain.

This study looked at the outcomes of trials enrolling more than 1,000 participants with no known history of cardiovascular diseases and which included a follow-up after twelve months. Participants included ones who took aspirin and other who took a placebo or had no treatment at all.
Advertisement

The results showed that:

  • Aspirin use was associated with an 11% lower risk of cardiovascular events.

  • Approximately 250 patients needed to be treated with aspirin for 5 years to prevent a single heart attack, stroke or cardiovascular death.

  • Aspirin use was associated with a 43% of major bleeding events, compared to those who did not take it.

  • Approximately one in 200 people treated with aspirin would have a major bleed.

  • No effect was seen with aspirin on new cancer diagnoses or deaths.


Lead author, Dr Sean Zheng, Academic Clinical Fellow in Cardiology at King's College London said: "This study demonstrates that there is insufficient evidence to recommend routine aspirin use in the prevention of heart attacks, strokes and cardiovascular deaths in people without cardiovascular disease.

"There has been more uncertainty surrounding what should be done in patients who are at higher risk of cardiovascular disease and in patients with diabetes. This study shows that while cardiovascular events may be reduced in these patients, these benefits are matched by an increased risk of major bleeding events.

"Aspirin use requires discussion between the patient and their physician, with the knowledge that any small potential cardiovascular benefits are weighed up against the real risk of severe bleeding."



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Gonorrhea
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Chemotherapy Chemotherapy Drugs Anticoagulants Healthy Living von Willebrand Disease Reye’s Syndrome Colon Polyps Hemophilia 

Recommended Reading
Aspirin to Lower Risk of Stroke in Women With History of Preeclampsia
Aspirin , the commonly used painkiller could reduce the risk of stroke in pregnant women having ......
Anticoagulants
Anticoagulants prevent the clotting of blood in our body. They are administered orally or via ......
Chemotherapy
‘Chemo’ means medicine or ‘drug’; ‘therapy’ means ‘treatment’. Chemotherapy refers to the use of cy...
Chemotherapy Drugs
Chemotherapy drugs perform like ‘magic bullets’ to destroy cancer cells in the body....
Colon Polyps
A colon polyp is a fleshy growth on the inside of the colon, also called the large intestine. In gen...
Hemophilia
Hemophilia is a rare single gene, X- linked disorder, which tends to run in families....
Reye’s Syndrome
Reye's syndrome is a medical emergency chiefly affecting children and teenagers and is marked by the...
von Willebrand Disease
von Willebrand's Disease (vWD) is an autosomal dominant inherited bleeding disorder that occurs from...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use