Artificial Bone Engineered by Bioengineers may Help Osteoarthritis Patients

by Rishika Gupta on  September 26, 2018 at 8:27 PM Research News
RSS Email Print This Page Comment bookmark
Font : A-A+

New bi-functional composite created by Bioengineers imitate he complex osteochondral structure of a joint, this in turn can help Patients with Osteoarthritis. The findings of this study are published in the journal of Kaunas University Of Technology.
 Artificial Bone Engineered by Bioengineers may Help Osteoarthritis Patients
Artificial Bone Engineered by Bioengineers may Help Osteoarthritis Patients

Researchers from the Faculty of Chemical Technology, Kaunas University of Technology (KTU), Lithuania are developing an artificial bone, which can be used for treating of the most common joint disease - osteoarthritis. The bi-functional composite imitates the complex osteochondral structure of a joint, i.e., both cartilage and bone tissues.

According to the World Health Organisation, around 10% of male and 18% of the female population over 60 are suffering from osteoarthritis. The onset of the condition is associated with thinning of the cartilage due to age; on average, people over 55 feel pain in 4 joints. The most common in the world inflammatory bone and cartilage disease, osteoarthritis, generally affects the knee, hip, spine, and tarsus.

While common treatment for osteoarthritis is pain or anti-inflammatory medication available as pills, syrups, creams or lotions, KTU chemists are offering a novel approach, i.e., using a bi-functional scaffold as an implant compensating cartilage and bone defects.

"A lot of people are suffering from painful joints, and the majority of them have osteoarthritis. To create new composites for solving this problem is especially challenging - cartilage tissue is renewing itself at a very slow rate, and it forms a complex structure together with a bone", says Simona Miseviciute, an applied chemistry undergraduate, who was conducting the experiment under the supervision of Dr Alisa Palaveniene.

The bi-functional scaffold, created at KTU aims to compensate for defects of both cartilage and bone. Made of several different substances - hydroxyapatite, gelatine, and chitosan - the scaffold imitates the complex osteochondral structure and functionality of the joint and fills the fractures of the two different tissues.

"Development of new scaffolds for regenerative engineering and implementing them in contemporary medicine is of utmost importance - to my knowledge, bi-functional scaffolds imitating complex osteochondral tissue currently are not used in medical practice," says Miseviciute.

One of the components of the new composite is gelatine, a cheap product commonly used in culinary and cosmetic industry. This clear, hard and almost tasteless substance, obtained from animal collagen, is highly biologically compatible, biodegradable and has low antigenic properties; its modification possibilities are numerous.

The scaffolds were modeled by layering polymer combinations, and the porous structure of a scaffold was achieved by lyophilisation, i.e., freeze drying.

Elemental analysis, bio imitational mineralization, degradability and water absorption of the composite scaffold were among the parameters measured during the experiment. The tests have shown that the samples were highly hydrophilic, which suggests functionality of the scaffold.

"To create bi-functional scaffolds for human bone engineering, interdisciplinary knowledge of chemistry, biology, pharmacy, anatomy is being used. The new research is aiming to solve the most urgent problems of today's aging society. Although these experiments are just a beginning of a great endeavor, we are happy to be keeping pace with global tendencies", says Dr. Palaveniene.

Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Advertisement

Recommended Reading

More News on:

Osteoarthritis Infantile Cortical Hyperostosis Hypermobility Syndrome Back Pain at Workplace: Prevention and Exercises Knee Replacement Surgery Diet, Nutrition and Supplements for Osteo-Arthritis and Rheumatoid Arthritis Hip Replacement Surgery Avascular Necrosis Renal Osteodystrophy / Mineral Bone Disorder Psoriatic Arthritis 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive