About My Health Careers Internship MedBlogs Contact us

Aortic Stenosis Best Treated With Transcatheter Aortic Valve Replacement (TAVR) in the Elderly

by Dr. Trupti Shirole on March 17, 2015 at 7:34 AM
Font : A-A+

 Aortic Stenosis Best Treated With Transcatheter Aortic Valve Replacement (TAVR) in the Elderly

Aortic stenosis is a common form of heart disease, in which the aortic valve does not open fully and decreases blood flow from the heart. Treatment options include open heart surgery, minimally invasive transcatheter aortic valve replacement (TAVR), or balloon aortic valvuloplasty (inserting a catheter into the groin and inflating a small balloon in the aortic valve to open it). A new study has found that TAVR to replace the aortic valve without doing open heart surgery, for people who are elderly or too frail for open heart surgery, has better outcomes after five years than patients who did not have surgery at all. TAVR may allow patients a better quality of life than the standard therapy of balloon aortic valvuloplasty.

Researchers followed 358 patients with severe aortic stenosis for five years. The patients' average age was 83-years, and they were evenly divided into two groups- one that had TAVR to replace their valve and one that had balloon aortic valvuloplasty but no surgery. It was found that after five years, 28% of the TAVR group were still alive, compared to only 6.4% of the standard therapy group. The study also found that those who had TAVR lived longer, with better symptom management, fewer hospital re-admissions and better functional status.


Study author Samir Kapadia, director of the Sones Cardiac Catheterization Laboratories at Cleveland Clinic, said, "This trial is the first, and will probably be the only, randomized aortic stenosis trial that includes a group of patients not treated with aortic valve replacement, since these results will make it unethical to treat severe aortic stenosis patients with medical therapy alone."

The study was published in The Lancet, and presented at the American College of Cardiology (ACC) annual conference in San Diego, California.

Another study released at the ACC conference showed promise for a new device, called TriGuard, that helps surgeons prevent dangerous debris from reaching the brain during TAVR, resulting in better cognitive scores for patients who underwent the procedure. The new device covers the three arteries that lead to the brain with a temporary mesh shield. A small trial involving 83 patients showed 22.2% of patients with the device had heart or brain complications in the week after surgery, compared to 31.6% without the protective mesh. Fewer patients died after the procedure in the group using the mesh, 2.2% compared to 5.3% in the control group.

Source: Medindia

News A-Z
News Category
What's New on Medindia
Emotional Healing
Psychosis Risk Related to Cat Parasite
Sedentary Behavior Precipitates Night-Time Hot Flashes
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cervical Spondylosis Aortic Valve Stenosis Infective Endocarditis Recent Advancements in Cardiac Surgery Bicuspid Aortic Valve Intestinal Atresia 

Recommended Reading
Aortic Valve Stenosis
Aortic valve Stenosis is an abnormal narrowing of the c valve. Symptoms include angina, and that of ...
Recent Advancements in Cardiac Surgery
Cardiac surgery is a formidable field in treating congenital heart diseases, valve replacements, ......
New Approach: Aortic Valve Implantation Combined With Coronary Artery Stenting
Aortic stenosis is a condition where the valve at the junction of the left ventricle and the aorta, ...
Four in Five Aortic Stenosis Patients Happy With the Treatment One Year After Surgery
Four in five patients who opted for surgical intervention for aortic valve disease in Germany ......
Bicuspid Aortic Valve
Bicuspid aortic valve is a congenital condition where the aortic valve has only two leaflets instead...
Cervical Spondylosis
Cervical spondylosis is a disorder in which there is abnormal wear on cervical vertebrae....
Infective Endocarditis
Infective endocarditis has been arbitrarily categorized as acute or subacute based on the length of ...
Intestinal Atresia
Intestinal atresia is a congenital condition where a segment of the intestine has failed to develop ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use