Certain nutritional supplements can increase the effectiveness of anti-depressants in people suffering from depression, suggest a team of researchers.
The findings showed that Omega 3 fish oils, S-adenosylmethionine (SAMe)*, methylfolate (bioactive form of folate) and Vitamin D, were all found to boost the effects of medication and can also be used as a mood enhancing therapy when taken with antidepressants.

The researchers from the University of Melbourne and Harvard analysed 40 clinical trials, alongside a systematic review of the evidence for using nutrient supplements -- known as nutraceuticals -- to treat depression in tandem with antidepressants.
"The difference for patients taking both antidepressants and Omega 3, compared to a placebo, was highly significant. This is an exciting finding because here we have a safe, evidence-based approach that could be considered a mainstream treatment," Sarris added in the paper published in American Journal of Psychiatry. They reported mixed results for zinc, vitamin C and tryptophan (an amino acid). Folic acid did not work particularly well, nor did inositol.
"Medical practitioners are aware of the benefits of omega 3 fatty acids, but are probably unaware that one can combine them with antidepressant medication for a potentially better outcome," Sarris stated. "We're not telling people to rush out and buy buckets of supplements. Always speak to your medical professional before changing or initiating a treatment," Sarris noted.
Source: IANS
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