After successfully conducting studies on mice, scientists have claimed that SRT1720, touted as an anti-aging pill, can be tested in human trials.
After successfully conducting studies on mice, scientists have claimed that SRT1720, touted as an "anti-aging pill," can be tested in human trials.
The new drug study from Sirtris Pharmaceuticals, Inc., based in Cambridge, Mass., claimed that SRT1720 activates the same receptor as the much-discussed resveratrol, the chemical in red wine that may slow some effects of aging.
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"We are very excited by these results. These compounds are mimicking calorie restriction and exercise while lowering levels of glucose and insulin in mice. It's a game changer," Discovery News quoted Michelle Dipp of Sirtris as saying.
In the study, the scientists overfed two groups of mice by about 40 percent, which can make up for almost eating 3,000 calories a day, and enough to pack on significant weight.
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However, the mice taking 500 mg of the drug, did not gain any weight. The cholesterol levels of the mice on the drug also improved.
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Dipp said that tests have shown that above 500 mg, the drug's effects plateau. SRT1720 has no known side effects.
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The SIRT1 receptor is also activated during caloric restriction diets, which have been shown to lengthen life span in multiple animal models, and during exercise.
SIRT1 receptors are found in mitochondria, often called the powerhouse of the cell because of all the energy they produce.
The study was published in the journal Cell Metabolism.
Source-ANI
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