Plans were made to achieve specific milestones in reaching the prime research goal of the National Plan to Address Alzheimer's Disease, to treat and prevent Alzheimer's disease and related dementias by 2025.
Experts from government, academia, industry, non-profit organizations put forward recommendations that provide a roadmap for an integrated, multidisciplinary research agenda necessary to inform priorities for Alzheimer's disease and related dementias.
Alzheimers Disease
Alzheimer''s disease is a progressive neurodegenerative disease affecting memory and thinking and making the person increasingly dependent on others.
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‘More than 80 leading experts joined to develop the research recommendations to achieve the prime research goal of the National Plan to Address Alzheimer's Disease, that is, to treat and prevent Alzheimer's disease and related dementias by 2025.’
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The recommendations are designed to guide continued efforts to build a collaborative, multi-stakeholder research environment capable of delivering urgently needed cures for people at all stages of the disease. The recommendations are a result of a multi-step, iterative process culminating in the Alzheimer's Disease Research Summit 2018: Path to Treatment and Prevention, which was convened by the National Institute on Aging (NIA), part of NIH at the U.S. Department of Health and Human Services, with support from the Foundation for the NIH.
A reccurring theme from the summit and in the recommendations is a precision medicine approach to Alzheimer's treatment and prevention--the ability to develop interventions that can address the underlying disease process as well as the disease symptoms and be tailored to a person's unique disease risk profile.
![Diseases Related to Old Age]( "Diseases Related to Old Age")
Ageing is referred to the accumulation of changes that brings a person closer to death.
"This is a critical time in Alzheimer's research, with new opportunities to build upon what we have learned," said NIA Director Richard J. Hodes, M.D. "We must continue to foster creative approaches that leverage emerging scientific and technological advances, establish robust translational infrastructure for rapid and broad sharing of data and research tools, and work with funding partners and other stakeholders to cultivate and sustain an open science research ecosystem."
The research recommendations build upon the framework established by previous summits in 2012 and 2015. They place emphasis on the approaches, tools, infrastructure and partnerships needed to understand disease heterogeneity by comprehensive study of disease risk and resilience across diverse populations; increase research rigor and reproducibility; and accelerate therapy development by integrating experimental and computational approaches and propagating open science practices.
The recommendations centered around several key topics:
Source: Eurekalert
Diseases Related to Old Age
Ageing is referred to the accumulation of changes that brings a person closer to death.
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"This is a critical time in Alzheimer's research, with new opportunities to build upon what we have learned," said NIA Director Richard J. Hodes, M.D. "We must continue to foster creative approaches that leverage emerging scientific and technological advances, establish robust translational infrastructure for rapid and broad sharing of data and research tools, and work with funding partners and other stakeholders to cultivate and sustain an open science research ecosystem."
The research recommendations build upon the framework established by previous summits in 2012 and 2015. They place emphasis on the approaches, tools, infrastructure and partnerships needed to understand disease heterogeneity by comprehensive study of disease risk and resilience across diverse populations; increase research rigor and reproducibility; and accelerate therapy development by integrating experimental and computational approaches and propagating open science practices.
The recommendations centered around several key topics:
- Developing a better understanding of the complex and multifactorial causes of disease
- Enabling precision medicine research needed to develop interventions that can address the underlying disease process, as well as the disease symptoms and be tailored to a person's unique disease risk profile for Alzheimer's disease
- Enhancing the research infrastructure and developing translational tools to accelerate therapy development
- Supporting the development of novel therapeutics that target the many facets of Alzheimer's disease
- Understanding the impact of the environment and its interaction with genetic and biological factors to advance effective prevention strategies for Alzheimer's disease
- Leveraging emerging digital technologies and big data approaches to improve our ability to discover early markers of disease, better track responsiveness to treatment and provide better care
- Bringing together multiple stakeholders to build a new research ecosystem based on the principles of open science.
Source: Eurekalert
Diet and Alzheimer´s Disease
Alzheimer''s begins with forgetfulness, but over time affects speech and coordination along with drastic behavioral changes. The right diet may lower your risk by 40%. So isn''t a diet change worth it?
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 Genetics of Alzheimer´s diseaseThere are numerous genes that have been discovered that are associated with Alzheimer's disease and indicate increased risk, aiding genetic counseling and better care. | Advertisement
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