Most antibiotics prescribed by dentists to prevent infections prior to dental visits are unnecessary, reports a new study. A new study conducted by researchers at the University of Illinois at Chicago and published in JAMA Network Open has found that 81% of antibiotics prescribed by dentists - who are among the top prescribers in the U.S., accounting for about 10% of all antibiotic prescriptions - to prevent infections prior to dental visits are unnecessary.
‘Almost 81 percent antibiotics prescribed by dentists to prevent infections prior to dental visits are unnecessary.’A team of researchers, led by Katie Suda, associate professor of pharmacy systems, outcomes and policy at the UIC College of Pharmacy, say that this surprising finding highlights the need for improved antibiotic stewardship in dental practices, especially those located in the Western U.S., which were associated with the highest rates of unnecessary prescribing.
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Using Truven, a national integrated health claims database, the researchers retrospectively analyzed dental visits occurring between 2011 and 2015. They compared antibiotic prescriptions -- which were dispensed prior to 168,420 dental visits -- to the number of high-risk cardiac patients who, per national guidelines, are the only patients recommended for antibiotics prior to a dental procedure.
They found that 81% of prescriptions did not align with the national guidelines and were provided for patients without high-risk cardiac conditions.
"Use of preventive antibiotics in these patients opens them up to the risks associated with antibiotic use -- increasing bacterial resistance and infections, for example -- when the evidence used to develop the guidelines suggests that the risks outweigh the benefits in most patients," said Suda, the corresponding author on the study.
The researchers also looked at dentists' antibiotic prescribing patterns by geography. They found that the Western U.S. and urban areas were more likely to have unnecessary prescribing. Among patients most likely to fill prescriptions for unnecessary antibiotics are those with prosthetic joint implants and those receiving clindamycin.
UIC's Susan Rowan, a dentist, worked with Suda on the research.
"I think dental providers should view this study, which is the first to look at preventive antibiotic prescribing for dental procedures and provide this type of actionable information, as a powerful call to action, not a rebuke."
The authors noted that because the study was limited to patients with commercial dental insurance, and the analysis used a broad definition of high-risk cardiac patients, the findings may actually underestimate unnecessary prescribing of antibiotics.