About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Alcohol Abuse and Mood Disorders can be Treated by Spinach-Protein

by Mohamed Fathima S on January 5, 2019 at 7:20 AM
Alcohol Abuse and Mood Disorders can be Treated by Spinach-Protein

New medications for millions of people dealing with alcohol use disorders, chronic pain, and mood disorders can be developed using spinach. A large protein present in the spinach aids in the development of medications, reveal researchers.

The study, led by researchers from the Purdue University, discovered two peptides which are naturally metabolic products of Rubisco -- a large protein found in many plants like spinach -- that may aid in the development of new medications.

Advertisement


"These disorders are currently not adequately managed," said Richard van Rijn, Assistant Professor at Purdue.

"Better medications that take a more holistic approach and produce fewer side effects will be beneficial.

"We discovered that these peptides selectively activate the known beneficial pathways without activating the 'side-effect pathways' of the receptor," van Rijn added.
Advertisement

The discovery, published in the European Neuropsychopharmacolgy, aims to develop molecules that only activate the cellular signalling pathways associated with their therapeutic effect.

Preclinical studies suggest that the peptides are orally bioavailable and able to penetrate the blood-brain barrier, both of which are necessary for a drug to effectively treat a disorder of the central nervous system, van Rijn said.

The researchers are actively pursuing synthetic and computational strategies to improve these peptides to make them more effective.

The rubiscolin peptides are also being investigated for their ability to regulate dietary intake and are even commercially available in anti-ageing skin products.



Source: IANS
Font : A-A+

Advertisement

Advertisement
Advertisement

Recommended Readings

Latest Alcohol & Drug Abuse News

US Drug Overdose Deaths Quadruple from 1999 to 2020
The United States is currently witnessing its highest overall mortality rates in over a century, driven in part by the surge in drug overdose fatalities.
Genes Linked to Psychostimulant Drug Addiction Identified
Deciphering genetic factors in brain responses to METH and COC enables personalized approaches to combat drug abuse.
Insomnia Drug DORA-12 Shows Promise in Preventing Oxycodone Relapse
Giving rats DORA-12 during oxycodone withdrawal reduced future drug-seeking behavior, showing promise for preventing opioid addiction and relapse in humans.
France is All Set to Put a 'Full Stop' to Disposable Vapes
Rising to 9.6% in 2021, daily vaping among New Zealand's 14-year-old students underscores a concerning youth trend.
Rising Marijuana Use Linked to Higher Blood and Urine Toxic Metal Levels
The research also revealed a 22 percent increase in cadmium levels among marijuana users.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
MediBotMediBot
Greetings! How can I assist you?MediBot
×

Alcohol Abuse and Mood Disorders can be Treated by Spinach-Protein Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests