New medications for millions of people dealing with alcohol use disorders, chronic pain, and mood disorders can be developed using spinach. A large protein present in the spinach aids in the development of medications, reveal researchers. The study, led by researchers from the Purdue University, discovered two peptides which are naturally metabolic products of Rubisco -- a large protein found in many plants like spinach -- that may aid in the development of new medications. Empowering Better Health Manage Your Diabetes Manage Your Hypertension Manage Your Kidney Health Manage Your Sex Life Health Tips "These disorders are currently not adequately managed," said Richard van Rijn, Assistant Professor at Purdue. ‘The peptides found in the spinach activate the beneficial pathways to treat the disorders without activating the 'side-effects' pathways.’ "Better medications that take a more holistic approach and produce fewer side effects will be beneficial. "We discovered that these peptides selectively activate the known beneficial pathways without activating the 'side-effect pathways' of the receptor," van Rijn added. The discovery, published in the European Neuropsychopharmacolgy, aims to develop molecules that only activate the cellular signalling pathways associated with their therapeutic effect. Preclinical studies suggest that the peptides are orally bioavailable and able to penetrate the blood-brain barrier, both of which are necessary for a drug to effectively treat a disorder of the central nervous system, van Rijn said. The researchers are actively pursuing synthetic and computational strategies to improve these peptides to make them more effective. The rubiscolin peptides are also being investigated for their ability to regulate dietary intake and are even commercially available in anti-ageing skin products. Source: IANS << Health Status Of Children Is Bound To Get Affected By Paren... World Braille Day Celebrated in UAE >> Recommended Reading Alcoholism Alcohol use disorder or alcoholism is an inability to control drinking. It can cause short term and long term physical, as well as psychological effects on the patient. READ MORE Mental Health - Neurosis vs Psychosis Mental well-being is a concern and abnormal coping of emotions can lead to neurosis or psychosis. Mental illnesses can range from depression, anxiety, phobias to schizophrenia and affective disorders. READ MORE Spinach Surprised why spinach is called a superfood? Spinach offers numerous health benefits and has disease prevention properties. READ MORE Drug Interaction with Alcohol The effects of alcohol, when consumed with certain drugs, can be life-threatening. Hence it is important to be aware of potential alcohol-drug interactions. READ MORE Alcohol Addiction and Women Social drinking amongst women has become a fad. Stop it before it finishes you. READ MORE Alcohol and Driving Alcohol and driving do not mix. Drunken driving is the cause of many deaths in the world. READ MORE Alcoholic Liver Disease Encyclopedia section of medindia gives general information about Alcoholic Liver Disease. READ MORE Amnesia Amnesia, is profound memory loss caused by a physical injury inflicted on the brain, by an infection or by a traumatic or emotional experience. READ MORE Bubbles and Brews - Alcohol Facts There is more to alcohol than mere intoxication. Infamous because of its social abuse but indispensable because of its many industrial applications. READ MORE Cannabis Cannabis has a long history of medicinal, recreational, and industrial use and comes from a bushy plant with thick sticky flowers called Cannabis Sativa READ MORE Drug Abuse The use of Drugs for reasons other than its prescribed recommendation, is known as Drug abuse or substance abuse. Drug abuse or substance abuse is initiated by various biological and social factors. READ MORE Is Your Man Moody? Women get confused by the behavior of men in their lives. It is time they realize that men too have frequent mood swings. READ MORE Pancreatitis Pancreatitis or inflammation of the pancreas may show up as acute pancreatitis or chronic pain. Alcohol consumption is the main offender. Treatment requires hospitalization and at times surgery. READ MORE Most Popular on Medindia Diaphragmatic Hernia Blood - Sugar Chart Post-Nasal Drip More News on: Alcoholic Liver DiseaseAlcoholismCannabisDrug AbuseAlcohol and DrivingBubbles and Brews - Alcohol FactsPancreatitisAmnesiaAlcohol Addiction and WomenIs Your Man Moody?