Air Pollution May Reduce the Efficacy Of Antibiotics

Air pollution can alter the efficacy of antibiotics, by increasing the potential of the bacteria to cause respiratory infections, finds new research.

"This work increases our understanding of how air pollution affects human health," said study lead author Julie Morrissey, Associate Professor at University of Leicester in Britain.

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‘Air pollution may make antibiotics less effective and increase the risk of respiratory infections.’

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"It shows that the bacteria which cause respiratory infections are affected by air pollution, possibly increasing the risk of infection," Morrissey said.

The study, published in the journal Environmental Microbiology, looked into how air pollution affects the bacteria living in our bodies, specifically the respiratory tract -- the nose, throat and lungs.

A major component of air pollution is black carbon, which is produced through the burning of fossil fuels such as diesel, biofuels, and biomass.

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The research showed that this pollutant changes the way in which bacteria grow and form communities, which could affect how they survive on the lining of our respiratory tracts and how well they are able to hide from, and combat, our immune systems.

The research focused on two human pathogens, Staphylococcus aureus and Streptococcus pneumoniae, which are both major causes of respiratory diseases and exhibit high levels of resistance to antibiotics.

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The research team found that black carbon alters the antibiotic tolerance of Staphylococcus aureus communities and importantly increases the resistance of communities of Streptococcus pneumoniae to penicillin, the front line treatment of bacterial pneumonia.

Furthermore, it was found that black carbon caused Streptococcus pneumoniae to spread from the nose to the lower respiratory tract, which is a key step in development of disease.

Source-IANS