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AI Helps Identify Key Patterns of Infant Movements

by Colleen Fleiss on Apr 4 2019 4:23 AM

Scientists created a method for an accurate extraction of children's movements (using a technique known as pose estimation), allowing for the construction of a simplified stick man (or skeleton) video.

AI Helps Identify Key Patterns of Infant Movements
University of Helsinki and University of Pisa researchers explored the possibility that a conventional video recording of an infant lying in bed could be transformed to a quantified analysis of infant movements. They collaborated with people from an //AI company based in Tampere, Neuro Event Labs, who were able to create a method for an accurate extraction of children's movements (using a technique known as pose estimation), allowing for the construction of a simplified "stick man" (or skeleton) video.
Subtle characteristics in the spontaneous movement of very young babies may reveal clinically important aspects of their neurodevelopment. Visual assessment of typical movement patterns (General movements, GM) by a clinical expert is known to be effective in early identification of e.g. cerebral palsy (CP).

A very early identification and subsequent therapeutic intervention would be highly beneficial for alleviating the neurodevelopmental impact of CP. Currently, a child is diagnosed with CP at much later age, typically between 6 months and 2 years of age. GM analysis holds promise in early detection of CP, however, it needs special expertise that is currently obtained through international teaching courses, which effectively limits the number of doctors or therapists with the relevant skills. In addition, GM analysis in its present form is based on visual assessment, which is always subjective.

"There is an urgent need for objective and automated methods. They would allow employing movement analyses at much wider scale, and make it accessible to basically most, if not all, children in the world," says Vanhatalo.

THE STICK MAN REVEALS THE ESSENTIALS

Next, the researchers gave the stick figure videos to doctors with GM expertise to see whether diagnostically crucial information was preserved in those videos.

Using the stick figure videos alone, the doctors were able to assign diagnostic groups in 95% of cases, proving that the clinically essential information had been preserved.

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The study shows that an automated algorithm may extract clinically important movement patterns from normal video recordings. These stick figure extractions can be directly used for quantitative analyses.

To demonstrate such potential, the researchers provided a proof of concept analysis where simple measures of stick figure movements showed clear differences between groups of infants with either normal or abnormal movements.

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Use of stick figure videos also enables world-wide sharing among research communities without privacy concerns. This has been a significant bottleneck in setting up multinational research activities within this domain.

"This will finally enable a genuinely Big Data kind of development for better quantitative movement analyses in infants," Vanhatalo states.

"Since this study, we have collected larger datasets, including 3D video recordings, and we are currently developing an AI-based method for infantile motor maturity assessment. The rationale is straightforward: there is a developmental issue with the child, if the computational assessment of the motor maturity does not match with the child's true age."

MOVEMENT ANALYSIS TELLS ABOUT NEURODEVELOPMENT AND EFFECTIVENESS OF THERAPEUTIC INTERVENTIONS

In addition to early CP detection, automated movement analyses have many potential applications in the assessment of infant neurological development.

"We could create one kind of functional growth chart," says Vanhatalo.

Movement analyses could also be used in diverse ways to improve therapeutic decisions. Such methods could provide quantitative means to objectively measure efficacy of different therapeutic strategies; one of the global hot topics in restorative medicine.

Automated movement analyses could also allow out-of-hospital screening of children to identify those that need further care, or to provide assurance of normality in cases with concern about child's development.

"Use of machine learning and artificial intelligence allows for the extraction of substantial amounts of clinically useful information from a simple home-grade video recording. The ultimate aim is to find methods that will make it possible to provide high and even quality infant healthcare everywhere in the world," Vanhatalo summarizes.

The study was a collaboration between researchers from University of Helsinki, Helsinki University Hospital, University of Pisa, Scuola Superiore San'Anna ja IRCCS Stella Maris Foundation from Pisa, Istituto Superiore di Sanità from Rome, and Neuro Event Labs Ltd from Tampere. The study was supported by Arvo and Lea Ylppö Säätiö, Finnish Pediatric Foundation, and Finnish Academy.

Source-Eurekalert


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