Aerobic exercise program is a good strategy to present alterations in kidney structure and urinary parameters caused by obesity and the development of diabetic [kidney disease] in obese rats.

‘Kidney (renal) disease is a common complication associated with type 2 diabetes, especially in people who are obese and do not exercise regularly.’

Researchers studied two groups of rats--both composed of a combination of lean and obese animals--to explore the effect of exercise on kidney disease risk factors. The "exercise" group was exercised on a treadmill for 45-60 minutes each day, five days a week. The "sedentary" group was trained for 15 minutes twice a week to mimic a human sedentary lifestyle. 




The most significant finding the researchers saw was an improvement in blood vessel health and overall kidney function. All of the obese rats, regardless of group, had hardening or scarring of the renal arteries, increased protein in the urine, and fat deposits within the filtering structures of the kidneys. However, the obese rats in the exercise group showed a reduction in these factors when compared to the sedentary obese rats. The exercised obese rats also had changes in bone composition--higher levels of calcium and copper, but lower concentrations of iron--when compared to the lean rats. These changes were not enough, however, to affect the risk of developing osteoporosis.
"We conclude that the introduction of an exercise program based in [aerobic interval training] is a good strategy to present alterations in kidney structure and urinary parameters caused by obesity and the development of diabetic [kidney disease] in obese Zucker rats," the researchers wrote.
Source-Eurekalert