About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Adults Who Experience Stroke Before Age 50 Have Higher Risk of Death Over Long-Term: Study

by Rukmani Krishna on March 23, 2013 at 12:42 AM
Font : A-A+

 Adults Who Experience Stroke Before Age 50 Have Higher Risk of Death Over Long-Term: Study

According to a study, in an examination of long-term mortality after stroke, adults 50 years of age and younger who experienced a stroke had a significantly higher risk of death in the following 20 years compared with the general population. The study can be found in the March 20 issue of JAMA.

"Stroke is one of the leading causes of mortality, with an annual 6 million fatal events worldwide. Stroke mainly affects elderly people, yet approximately 10 percent of strokes occur in patients younger than 50 years. Despite this considerable proportion, only limited data exist on long-term prognosis after stroke in adults aged 18 through 50 years. It is exactly this long-term prognosis that is particularly important in adults in these ages, given that they have a long life expectancy during a demanding time of life in which they are beginning their families and building their careers," according to background information in the article.

Advertisement

Loes C. A. Rutten-Jacobs, M.Sc., of Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands, and colleagues conducted a study to investigate long-term mortality and cause of death after first acute stroke among adults 18 through 50 years of age and to compare this with nationwide age- and sex-matched mortality rates. The study included adults with transient ischemic attack (TIA), ischemic stroke, or hemorrhagic stroke admitted to a medical center between January 1980 and November 2010. The survival status of 959 patients with a first-ever TIA (n=262), ischemic stroke (n =606), or intracerebral hemorrhage (n=91) was assessed as of November 1, 2012. Average follow-up duration was 11.1 years. Observed mortality was compared with the expected mortality, derived from mortality rates in the general population with similar age, sex, and calendar-year characteristics.

During the follow-up period, 192 patients (20.0 percent) had died. The researchers found that the cumulative 20-year mortality risk was 24.9 percent for patients with TIA; 26.8 percent for patients with ischemic stroke; and 13.7 percent for patients with ICH. Analysis of the data indicated that after surviving the first 30 days after ischemic stroke, the cumulative mortality was increased compared with expected based on nationwide population mortality data. "This mortality remained at this higher level even in the second and third decade after young [18-50 years of age] stroke. In patients who survived the first 30 days after an ICH, mortality gradually coincided with that expected."
Advertisement

The cumulative 20-year mortality for ischemic stroke among 30-day survivors was higher in men than in women (33.7 percent vs. 19.8 percent).

The authors point out that their study showed an excess in mortality compared with the general population (in which half of deaths were attributable to a vascular cause), even decades after stroke. "This may suggest that the underlying (vascular) disease that caused the stroke at relatively young age continues to put these patients at an increased risk for vascular disease throughout their lives. It may also be noted that risk factors indicated in the study group, such as smoking and alcohol consumption, seem likely to confer risk as well."

"Although data are currently lacking, the observation of long-term increased risk for vascular disease could have important implications for the implementation of secondary prevention (both medical and lifestyle) treatment strategies. Future studies should address the role of this stringent implementation in these patients with young stroke."

Source: Newswise
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Cochlear Implants may Consequently Drive Hearing Loss
E-cigarettes Use Linked to Erectile Dysfunction
Memory Loss - Can it be Recovered?
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Bell´s Palsy Diet Lifestyle and Heart Disease Mitral Valve Stenosis And Mitral Valve Replacement Congenital Heart Disease Stress and the Gender Divide Death Facts Stroke Facts Stroke Hyperventilation Bereavement 

Recommended Reading
Heat Stroke
Heat stroke is caused when body temperature or hyperthermia exceeds 40.6°C or 105.1°F. Heat stroke ...
How to Deal with a Stroke
Stroke is a brain attack, which occurs when the blood supply to the brain is interrupted. It ......
Stress and the Gender Divide
Stress has become entwined in the current lifestyle of a young working couple and has resulted in .....
Stroke
Stroke can cause permanent disability and it is important to recognize its early warning signs to .....
Bereavement
Bereavement refers to grief, pain and sadness following the loss of a loved one, especially during t...
Congenital Heart Disease
Heart diseases that are present at birth are called “ Congenital heart diseases”....
Hyperventilation
Hyperventilation occurs when a person breathes in excess to the body’s requirement....
Mitral Valve Stenosis And Mitral Valve Replacement
Mitral valve replacement is a surgical heart procedure to correct either the narrowing (stenosis) or...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use