About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Adult Working Memory may be Adversely Affected by Amphetamine Use in Adolescence

by Rajshri on October 23, 2009 at 7:56 PM
Font : A-A+

 Adult Working Memory may be Adversely Affected by Amphetamine Use in Adolescence

Researchers have revealed that rats exposed to high doses of amphetamines at an age that corresponds to the later years of human adolescence display significant memory deficits as adults even after the exposure ends.

The declines in short-term or "working" memory are most pronounced when the rats are exposed during adolescence, rather than as adults, the researchers found.

Advertisement

"Animals that were given the amphetamine during the adolescent time period were worse at tasks requiring working memory than adult animals that were given the same amount of amphetamine as adults," said psychology professor Joshua Gulley, who led the study with graduate student Jessica Stanis. "This tells us that their working memory capacity has been significantly altered by that pre-exposure to amphetamine."

Gulley and his colleagues will present their findings Wednesday (Oct. 21) at the annual meeting of the Society for Neuroscience in Chicago.

The researchers tested two types of amphetamine exposure: intermittent (a steady dose every other day) and "binge-escalation," in which increasing amounts of the drug were given over a period of four days, followed by a simulated binge - a high dose every two hours for eight hours on the fifth day.
Advertisement

The findings reveal some of the potential long-term consequences of amphetamine abuse by adolescents and also may be relevant to those taking amphetamines for therapeutic purposes, such as for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Gulley cautions that the doses given to the rats are on the high end of what an older, larger adolescent might receive as a therapeutic dose, and that further study is needed to tease out the implications for human health.

The concerns are most robust for adolescents who abuse amphetamines, Gulley said, as they may use much higher doses than those who are prescribed drugs that contain amphetamines.

"Adolescence is a time when the brain is continuing to develop into its mature form, so drug exposure during this critical period could have long-lasting, negative consequences," he said. "Our findings reveal that adolescents are particularly sensitive to the adverse effects of amphetamine on cognitive function and that these effects can persist well after drug use is discontinued."



Source: Eurekalert
RAS
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
First-Ever Successful Pig-To-Human Kidney Transplantation
World Osteoporosis Day 2021 -
Spirituality and Mental Health
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Abuse Screening Test Teenage Drug Detox Brain Exercises to Improve Memory Foods to Improve Memory Power Ways to Improve your Intelligence Quotient (IQ) Quick and Easy Ways to Memorize Things 7 Ways How Writing by Hand Improves Brain Power 

Recommended Reading
Alzheimers Disease
Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and ......
Schizophrenia
Schizophrenia is a mental disorder characterized by symptoms of thought, behavior and social ......
Dyslexia
Dyslexia is a reading disability that occurs when the brain does not properly recognize and process ...
Another Necessary Step in Memory Formation Identified
Another component in the chain of actions that take place in the neurons, when the brain is in the ....
7 Ways How Writing by Hand Improves Brain Power
Do you want to sharpen the way your brain works? Try writing by hand to sharpen your mind and increa...
Brain Exercises to Improve Memory
An active brain can certainly help in improving memory by strengthening the connections between neur...
Drug Detox
Drug detoxification (or drug detox) is a process that helps drug addicts to give up drugs with less ...
Foods to Improve Memory Power
Eating healthy nutritious foods can help improve memory power and prevent brain-related illness. Eat...
Quick and Easy Ways to Memorize Things
You can train your brain to memorize things faster. If you’re thinking about how to train the brain,...
Ways to Improve your Intelligence Quotient (IQ)
Intelligence quotient (IQ) is a psychological measure of human intelligence. Regular physical and me...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use