The study, which examined the urinary patterns of sleep-deprived volunteers, found that a lack of sleep increases urinary output and salt in urine. However, the findings of the study were found to be more prevalent in males than females.
For the study, Danish researchers made twenty healthy volunteers (ten males; ten females; 19-35 years of age) undergo two 24-hour circadian in-patient studies under standardized conditions for diet and fluid intake. Participants were sleep deprived during one of the two sessions in a randomized sequence.
The team recorded the blood pressure and heart rate of the participants every hour using a non-invasive blood pressure monitor. Electrolytes, osmolarity, creatine and urea were evaluated in plasma and urine.
The results showed that there were no noteworthy differences in the quantity or contents of the daytime urine examined in both experimental periods. However, following the sleep deprivation period, both genders produced strikingly larger amounts of urine, and this effect was considerably more pronounced in males than females.
Apart from the effect on urine productions, the researchers found that during night time, acute sleep deprivation affected other areas as well.
These included a reduced fall in blood pressure, lower levels of sodium regulating hormones, excessive excretion of osmoles (sodium and potassium), and a change in the body's hemodynamics.