About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Acne in Adults is Caused by Combo of Two Abnormal Factors: Study

by VR Sreeraman on August 7, 2007 at 5:03 PM
Font : A-A+

Acne in Adults is Caused by Combo of Two Abnormal Factors: Study

A new study conducted by researchers at the University of California has found that it is not just one, but a combination of two abnormal factors, that cause adult acne or rosacea.

Adult acne is a common condition which affects fair-skinned people of mostly north-western European descent. It begins as erythema (flushing and redness) on the central face and across the cheeks, nose, or forehead but can also less commonly affect the neck and chest.

Advertisement

It is linked with a type of bacteria, and antibiotics are prescribed to treat its symptoms. It, however, worsens over time.

During the study, Richard L. Gallo and his colleagues first observed in the laboratory that small proteins of the body's host defence system called anti-microbial peptides caused the exact symptoms like redness, an increase in visible blood vessels, bumps or pimples, that rosacea did.
Advertisement

"When we then looked at patients with the disease, every one of them had far more peptides than normal." Nature magazine quoted Gallo as saying.

The researchers examined the source of these molecules to know why these patients had abnormal peptides.

The precursor form of these peptides, called cathelicidin, is known to guard the skin against infection. A deficiency of cathelicidin correlates with increased infection in other skin diseases.

The study found the opposite in rosacea patients, as excessive cathelicidin of a different form was present in their skin.

Rosacea patients also had high levels of enzymes called stratum corneum tryptic enzymes (SCTE). These enzymes turned the precursor into the disease-causing peptide.

The inflammation in the skin of the mice increased when the researches injected them with cathelicidin peptides, indicating that these abnormalities can cause the disease.

"Too much SCTE and too much cathelicidin leads to the abnormal peptides that cause the symptoms of this disease. Antibiotics tend to alleviate the symptoms of rosacea in patients because some of them work to inhibit these enzymes. Our findings may modify the therapeutic approach to treating rosacea, since bacteria aren't the right target," Gallo said.

Source: ANI
LIN/J
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Contraceptive Pills in Polycystic Ovary Syndrome (PCOS) Curtail Type 2 Diabetes Risk
Mushroom May Help Cut Down the Odds of Developing Depression
How to Battle Boredom during COVID
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Acne Stress Relief Through Alternative Medicine Skin Disease Rashes Symptom Evaluation Exfoliate Hidradenitis Suppurativa Top 10 Ways to Clear Acne Blackheads / Comedones Ten Most Common Skin Disorders Foods That Can Make Skin Oily 

Recommended Reading
Home Remedies for Acne | Pimples
Home remedies offer you an herbal and natural method to treat acne effectively. It also explains ......
Acne
Acne vulgaris, popularly known as ‘pimples’ or ‘zits’ is a skin condition affecting most teenagers....
Blackheads / Comedones
Blackheads or comedones are skin abrasions formed due to clogging of hair follicle with excess sebum...
Foods That Can Make Skin Oily
Wrong food choices and poor skin care contribute to oily skin and acne. Avoiding foods that secrete ...
Hidradenitis Suppurativa
Hidradenitis suppurativa (HS) or Acne Inversa is severe form of chronic acne of the sweat glands whi...
Rashes Symptom Evaluation
The lesions in rashes vary from small skin discolorations to large fluid-filled bullae....
Skin Disease
Skin diseases also known as dermatologic disorders are many in number and so are their causes. The c...
Ten Most Common Skin Disorders
Skin problems cause discomfort and embarrassment necessitating effective treatment. Here are 10 comm...
Top 10 Ways to Clear Acne
Living with acne can be tough, but not anymore. Here we bring you the 10 best ways to deal with acne...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use