A peptide that binds to Bcl 2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer has been developed by US scientists.
The progress made by scientists at Burnham Institute for Medical Research takes then a step closer to creating new cancer treatments.
About Cancer in Women
Cancer is one of the frequently talked about and most feared disease that falls under the genre of lifestyle diseases that have evolved, rather rapidly, in the past two decades.
Cancer is one of the frequently talked about and most feared disease that falls under the genre of lifestyle diseases that have evolved, rather rapidly, in the past two decades.
The researchers have revealed that the peptide called NuBCP-9, and its mirror-image molecule work on Bcl-2 like a molecular switch, converting it into a pro-apoptotic protein, and inducing cell death in cancer cells.
"Our results provide insight into Bcl-2 conversion and identify a new direction for Bcl-2-based drug leads and cancer drug development," said Dr. Xiao-kun Zhang, who co-authored the paper with Dr. Arnold Satterthwait and others.
Nur77 often moves from the nucleus to mitochondria, in response to different death signals, where it binds to Bcl-2, changing its shape and function.
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Oral Cancer | Mouth Cancer - Types, Causes, Symptoms, Diagnosis, Treatment & Prevention
Oral cancer is a cancer that develops in any part of the mouth. It is more common in men over 40.
Oral cancer is a cancer that develops in any part of the mouth. It is more common in men over 40.
Source-ANI
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Pancreatic Cancer - All About the Disease, its Diagnosis and Management
Pancreatic cancer often involves its exocrine part. It grows aggressively, and often detected late. Treatment options include surgery, radiation and chemotherapy.
Pancreatic cancer often involves its exocrine part. It grows aggressively, and often detected late. Treatment options include surgery, radiation and chemotherapy.
