Short tandem repeat (STR) genotyping and p57 immunohistochemistry have been used by researchers from The Johns Hopkins Medical Institutions to distinguish hydatidiform moles.
The related report by Murphy et al "Molecular Genotyping of Hydatidiform Moles: Analytic Validation of a Multiplex Short Tandem Repeat (STR) Assay," appears in the November 2009 issue of The Journal of Molecular Diagnostics.
Ectopic Pregnancy - Causes - Symptoms - Diagnosis - Treatment - FAQs
When the fertilization of the ovum occurs in a place other than the uterus, the condition is called ectopic pregnancy. This is a life-threatening condition, ectopic pregnancy surgery can help.
When the fertilization of the ovum occurs in a place other than the uterus, the condition is called ectopic pregnancy. This is a life-threatening condition, ectopic pregnancy surgery can help.
CHMs, PHMs, and non-molar specimens (NMs) have different risks for persistent GTD, and thus differentiation is important for clinical treatment of patients. Morphological diagnosis results in high inter- and intra-observer variability; therefore, Murphy et al explore using genetic features to differentiate CHMs, PHMs, and NMs. They found that STR genotyping and p57 immunohistochemistry, by identifying the parental source of particular alleles, can distinguish CHMs, PHMs, and NMs and have developed an algorithm for the interpretation of STR data.
Dr. Murphy and her colleague Dr Brigitte Ronnett "have applied this algorithm in routine practice to ensure accurate diagnosis of hydatidiform moles. In doing so, they have determined that the genetics of molar specimens can be more complicated than traditionally thought." Drs. Murphy and Ronnett are now working to "discover additional risk factors for GTD, in order to identify women who may require chemotherapy."
Home Pregnancy Test - Principle - Advantages - Perform - FAQs
A home pregnancy test is a test done to find out if one is pregnant or not in the relative comforts of the home.
A home pregnancy test is a test done to find out if one is pregnant or not in the relative comforts of the home.
Source-Eurekalert
RAS
Psychological Changes in Pregnancy - How to Deal - FAQs - Reference
Pregnancy is an experience of growth, change, enrichment and challenge. During the 40 weeks of pregnancy, the expectant mother will go through several physical and emotional changes.
Pregnancy is an experience of growth, change, enrichment and challenge. During the 40 weeks of pregnancy, the expectant mother will go through several physical and emotional changes.
Pregnancy and Diet/Diet during Pregnancy – Healthy Foods, Foods to Avoid
Pregnant women should pay special attention to their diet. The diet before and during pregnancy should be rich in calories, proteins, vitamins and minerals.
Pregnant women should pay special attention to their diet. The diet before and during pregnancy should be rich in calories, proteins, vitamins and minerals.
