Men who are obese are at an increased risk of their prostate cancer worsening than slim men.
This is even after they were treated with hormone therapy to suppress tumour growth. Researchers, led by Christopher J. Keto, urologic fellow at Duke University Medical Center, made their conclusions after looking 287 men whose diseased prostates had been removed during the period between 1988-2009.
Since their cancers had reappeared, the men had also been given androgen deprivation therapy (ADT). The chemical inhibits production of the male hormone testosterone, which fuels prostate tumours.
The study revealed that men who were overweight had a three-fold increased risk of cancer progression compared to normal-weight men, despite receiving the same treatment.
In addition, obese men had more than a three-fold increased risk of cancer spreading to the bone compared to normal-weight men.
The research was presented at the American Urological Association annual meeting.