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Human Trial to Test Cancer Cure on the Anvil

by Rajshri on Jun 30 2008 2:12 PM

Scientists at Wake Forest University Baptist Medical Center will be soon starting a human trail to asses if a cancer cure that worked in mice will show the same results in humans as well.

The basic treatment includes transfusing white blood cells, called granulocytes into patients having advanced cancer. A similar treatment regimen in mice had worked successfully.

"In mice, we've been able to eradicate even highly aggressive forms of malignancy with extremely large tumors," Zheng Cui, Ph.D., lead researcher and associate professor of pathology said. "Hopefully, we will see the same results in humans. Our laboratory studies indicate that this cancer-fighting ability is even stronger in healthy humans."

The researchers are seeking 500 healthy individuals to donate white blood cells for the trial. Among them the 100 healthiest ones who have the highest level of cancer-fighting activity in their WBCs will be chosen to donate these cells.

"The difference between our study and the traditional white cell therapy is that we're selecting the healthy donors based on the cancer-killing ability of their white blood cells," said Cui. The participants will be monitored after three months to asses if there are any clinical benefits from the therapy.

Source-Medindia
RAS/L


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