Flu Pandemics may be Caused by Changing Weather Patterns

The changing migration patterns of birds due to La Nina weather patterns in the equatorial Pacific may trigger the development of novel and lethal flu strains, a new study has shown.

Worldwide pandemics of influenza caused widespread death and illness in 1918, 1957, 1968 and 2009.

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A new study examining weather patterns around the time of these pandemics finds that each of them was preceded by La Nina events.

The study's authors - Jeffrey Shaman of Columbia University's Mailman School of Public Health and Marc Lipsitch of the Harvard School of Public Health-noted that the La Nina pattern is known to alter the migratory patterns of birds, which are thought to be a primary reservoir of human influenza.

To examine the relationship between weather patterns and influenza pandemics, the researchers studied records of ocean temperatures in the equatorial Pacific in the fall and winter before the four most recent flu pandemics emerged.

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They found that all four pandemics were preceded by below-normal sea surface temperatures-consistent with the La Nina phase of the El Nino-Southern Oscillation.

This La Nina pattern develops in the tropical Pacific Ocean every two and seven years approximately.

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The authors also cited other research showing that the La Nina pattern alters the migration, stopover time, fitness and interspecies mixing of migratory birds. These conditions could favour the kind of gene swapping-or genetic reassortment-that creates novel and therefore potentially more variations of the influenza virus.

"We know that pandemics arise from dramatic changes in the influenza genome. Our hypothesis is that La Nina sets the stage for these changes by reshuffling the mixing patterns of migratory birds, which are a major reservoir for influenza," said Jeffrey Shaman, PhD, Mailman School assistant professor of Environmental Health Sciences and co-author of the tudy.

The study has been published online in PNAS.

Source-ANI