A recent study has revealed that exposure to environmental factors in early life may influence the risk of testicular cancer.
The study led by Dr. Charlotte Myrup, of Statens Serum Institute in Copenhagen, Denmark evaluated the occurrence of testicular cancer among first- and second- generation immigrants to Denmark and residents of Danish ancestry.
The team accumulated the data on 2.1 million men who lived in Denmark between 1968 and 2003, which included 344,444 immigrants to Denmark and 56,189 men born in Denmark to immigrant parents.
The findings revealed that the risk of testicular cancer was considerably lower among first-generation immigrants to Denmark in contrast to the men born in Denmark to immigrant parents and Danish men with Danish parents.
Around 4,216 cases of testicular cancers were reported among the group with 166 cases of first-generation immigrants and 13 cases of the second-generation immigrants.
"The difference in testicular cancer rates among men born to foreign parents inside Denmark compared with those immigrating to Denmark as children or adults point to the possibility of environmental influences in utero," wrote the authors.
The results showed that the relative risk of testicular cancer was 63 percent lower among first-generation immigrants, however there was no statistical difference in risk among second-generation immigrants, compared with men of Danish ancestry.
The study is published in the Journal of the National Cancer Institute.