A dietary ingredient derived from a melon, which is rich in antioxidant superoxide dismutase enzymes, could relieve stress, according to a study.
In the double-blind, randomised, placebo-controlled trial, researchers found that the supplement decreased the signs and symptoms of perceived stress and fatigue in healthy volunteers.
For the study, Marie-Anne Milesi from Seppic, France, worked with a team of researchers to evaluate its anti-stress effects in 70 volunteers.
"Several studies have shown that there is a link between psychological stress and intracellular oxidative stress. We wanted to test whether augmenting the body's ability to deal with oxidative species might help a person's ability to resist burnout. The 35 people in our study who received capsules containing superoxide dismutase showed improvement in several signs and symptoms of perceived stress and fatigue," she said.
Volunteers who received inactive starch capsules showed a strong placebo effect.
However, the improvements seen in the supplement group were significantly greater, especially after 28 days.
"The placebo effect was only present during the first 7 days of supplementation and not beyond. It will be interesting to confirm these effects and better understand the action of antioxidants on stress in further studies with a larger number of volunteers and a longer duration," said Milesi.
The study has been published in BioMed Central's open access Nutrition Journal.