Lung diseases like asthma and pulmonary hypertension could arise due to crosstalk between cells lining the lung (epithelial cells) and airway smooth muscle cells.
Already, it is known that such crosstalk is important in lung development.
Scientists Hope Artificially Created 3-D Airway Spheres Will Help Study Lung Disease
In what may help improve the scientific understanding of lung diseases, Duke University Medical Center scientists have found that a single lung cell can become one of two very different
In what may help improve the scientific understanding of lung diseases, Duke University Medical Center scientists have found that a single lung cell can become one of two very different
The team, led by Edward Morrisey and Ethan David Cohen, used numerous in vivo gain- and loss-of-function approaches to demonstrate that a Wnt7b/Tnc/Pdgfr crosstalk pathway was important for mouse smooth muscle development.
They also showed that lung epithelial cells exclusively express Wnt7b and the developing airway smooth muscle cells express Pdgfr.
Childhood Exposure to Ultrafine Air Pollution Linked to Lung Disease in Adulthood
A new study has revealed that early exposure to environmental factors such as allergens, pollutants, and respiratory viruses might put infants at an increased risk of lung disease in adulthood.
A new study has revealed that early exposure to environmental factors such as allergens, pollutants, and respiratory viruses might put infants at an increased risk of lung disease in adulthood.
Thus indentifying the Wnt/Tnc/Pdgfr crosstalk pathway is equally important in both lung development and adult lung disease.
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Cystic Fibrosis Lung Disease Treated By Common Cold Virus?
Scientists from the University of North Carolina at Chapel Hill School of Medicine have found what may be the most efficient way to deliver a corrected gene to lung cells derived
Scientists from the University of North Carolina at Chapel Hill School of Medicine have found what may be the most efficient way to deliver a corrected gene to lung cells derived
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Study Says Protein may Indicate Presence of Rare Lung Disease
A protein in the lungs that can help in determining progression of the rare lung disease Idiopathic Pulmonary Fibrosis (IPF) has been discovered
A protein in the lungs that can help in determining progression of the rare lung disease Idiopathic Pulmonary Fibrosis (IPF) has been discovered
