Scientists hope to put British people on test to see if brain-training can help prevent debilitating diseases like Alzheimer's.
The Alzheimer's Society and the BBC are running Brain Test Britain to assess whether mind-training-such as with hand-held computers-can really help ward off dementia.
The BBC is launching the programme on BBC1 tonight as part of the show 'Bang Goes The Theory.'
The test will investigate brain-training's impact on "mental fitness".
However, the initial results of the study conducted by King's College London and Cambridge University will be announced early next year, but a nine-month trial will continue to assess potential long-term effects.
"I always wondered if any of these brain-training gadgets and games really work," the Daily Express quoted Children's TV presenter Richard McCourt, of Dick and Dom, an Alzheimer's Society ambassador as saying.
"I'm looking forward to being trained up and finding out more about how our brains function.
The more we know about the brain, the nearer we'll come to finding a cure for dementia - and that's the reason why I want to be involved," he added.